STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gnd6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa)    
Predicted Functional Partners:
gntV
Gluconokinase; Similar to Escherichia coli thermosensitive gluconokinase IdnK or GntV or b4268 SWALL:IDNK_ECOLI (SWALL:P39208) (187 aa) fasta scores: E(): 5.8e-34, 62.02% id in 158 aa.
   
 0.992
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
 0.986
rpe
Ribulose-phosphate 3-epimerase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri ribulose-phosphate 3-epimerase Rpe or Dod or b3386 or c4156 or z4739 or ecs4228 or sf3404 SWALL:RPE_ECOLI (SWALL:P32661) (225 aa) fasta scores: E(): 5.1e-71, 83.92% id in 224 aa.
   
 0.946
rpiA
Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
  
 
 0.945
ECA3507
Putative exported protein; Similar to Bradyrhizobium japonicum Blr0368 protein Blr0368 SWALL:BAC45633 (EMBL:AP005936) (398 aa) fasta scores: E(): 5.2e-15, 43.73% id in 359 aa, and to Yersinia pestis hypothetical protein ypo1149 or y3033 SWALL:Q8ZGX4 (EMBL:AJ414146) (334 aa) fasta scores: E(): 3.3e-12, 36.31% id in 347 aa.
 
  
 0.928
pgl
Conserved hypothetical protein; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate.
 
  
 0.925
edd
Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
   
 0.924
rpiB
Ribose 5-phosphate isomerase; Involved in catabolism of D-apiose. Catalyzes the isomerization of D-erythrulose 4-phosphate to D-erythrose 4-phosphate.
    
 0.916
kduD
2-keto-3-deoxygluconate oxidoreductase; Similar to Pectobacterium carotovorum subsp. atrosepticum 2-keto-3-deoxygluconate oxidoreductase KduD SWALL:Q8KHI5 (EMBL:AJ506783) (253 aa) fasta scores: E(): 6.3e-94, 98.41% id in 253 aa, and to Erwinia chrysanthemi 2-deoxy-D-gluconate 3-dehydrogenase KduD SWALL:KDUD_ERWCH (SWALL:Q05528) (253 aa) fasta scores: E(): 4.4e-87, 89.72% id in 253 aa.
  
 0.822
ECA0189
Putative mandelate racemase / muconate lactonizing enzyme; Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.
     
  0.800
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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