Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA1448Putative exported protein; Similar to Shigella flexneri orf, conserved hypothetical protein yjbh or sf4176 SWALL:AAN45597 (EMBL:AE015426) (698 aa) fasta scores: E(): 1e-142, 52.89% id in 673 aa, and to Escherichia coli hypothetical lipoprotein yjbh precursor yjbh or b4029 SWALL:YJBH_ECOLI (SWALL:P32689) (698 aa) fasta scores: E(): 5.8e-142, 53.04% id in 673 aa. (710 aa)    
Predicted Functional Partners:
ECA1447
Putative exported protein; Similar to Escherichia coli hypothetical protein ymcb precursor ymcb or b0985 SWALL:YMCB_ECOLI (SWALL:P75883) (248 aa) fasta scores: E(): 3.6e-08, 31% id in 258 aa, and to Shigella flexneri orf, conserved hypothetical protein ymcb or sf0987 SWALL:AAN42615 (EMBL:AE015127) (248 aa) fasta scores: E(): 3.6e-08, 32.04% id in 259 aa.
  
 0.988
ECA1446
Putative lipoprotein; Similar to Vibrio cholerae DNA for otn region genes OtnE SWALL:Q56656 (EMBL:X90547) (229 aa) fasta scores: E(): 1.1e-22, 33.64% id in 211 aa, and to Shigella flexneri orf, conserved hypothetical protein yjbf or sf4178 SWALL:AAN45599 (EMBL:AE015426) (222 aa) fasta scores: E(): 4.3e-20, 34.52% id in 223 aa.
 
  
 0.968
ECA1445
Putative membrane protein; Similar to Vibrio parahaemolyticus hypothetical protein vp0218 SWALL:BAC58481 (EMBL:AP005073) (72 aa) fasta scores: E(): 0.015, 48.71% id in 78 aa, and to Vibrio vulnificus hypothetical protein vv10787 SWALL:Q8DE18 (EMBL:AE016799) (86 aa) fasta scores: E(): 0.58, 48.91% id in 92 aa.
       0.554
ECA2009
Putative exported protease; Similar to Shigella flexneri orf, conserved hypothetical protein sf1619 SWALL:AAN43202 (EMBL:AE015183) (273 aa) fasta scores: E(): 1.1e-59, 57.35% id in 272 aa, and to Escherichia coli putative protease ydgd precursor ydgd or b1598 SWALL:YDGD_ECOLI (SWALL:P76176) (273 aa) fasta scores: E(): 1.8e-59, 57.35% id in 272 aa; Belongs to the peptidase S1B family.
 
     0.551
ECA0705
Partial CDS. Similar to an internal region of Agrobacterium tumefaciens non-ribosomal peptide synthetase MtaD or atu3682 or agr_l_2311 SWALL:Q8U9P4 (EMBL:AE009297) (2399 aa) fasta scores: E(): 0.00074, 32.99% id in 97 aa, and to Anabaena sp. peptide synthetase all2648 SWALL:Q8YTR5 (EMBL:AP003590) (2588 aa) fasta scores: E(): 0.0032, 34.4% id in 93 aa.
     
 0.536
wza
Putative polysaccharide export protein; Similar to Escherichia coli, and Escherichia coli O157:H7 putative polysaccharide export protein Wza precursor Wza or b2062 or z3227 or ecs2867 SWALL:WZA_ECOLI (SWALL:P76388) (379 aa) fasta scores: E(): 3.3e-105, 68.86% id in 379 aa.
 
  
 0.533
aas
Aas bifunctional protein [includes: 2-acylglycerophosphoethanolamine acyltransferase; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
   
 0.501
wzb
Probable protein-tyrosine-phosphatase; Similar to Salmonella typhimurium low molecular weight protein-tyrosine-phosphatase Wzb or stm2117 SWALL:WZB_SALTY (SWALL:Q9F7B2) (149 aa) fasta scores: E(): 1.5e-34, 65.73% id in 143 aa, and to Erwinia amylovora probable low molecular weight protein-tyrosine-phosphatase AmsI SWALL:AMSI_ERWAM (SWALL:Q46630) (144 aa) fasta scores: E(): 5.8e-37, 69.44% id in 144 aa.
 
  
 0.497
fliT
Flagellar protein; Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
  
     0.489
rcsD
Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
 
   
 0.465
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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