STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1456Putative aldehyde dehydrogenase; Similar to Pseudomonas aeruginosa methylmalonate-semialdehyde dehydrogenase [acylating] MmsA or pa3570 SWALL:MMSA_PSEAE (SWALL:P28810) (496 aa) fasta scores: E(): 2.6e-87, 49.68% id in 483 aa, and to Yersinia pestis putative aldehyde dehydrogenase ypo2577 or y1146 SWALL:Q8ZDI9 (EMBL:AJ414152) (508 aa) fasta scores: E(): 1.9e-151, 78.62% id in 510 aa. (503 aa)    
Predicted Functional Partners:
fadJ
Putative fatty acid oxidation complex alpha subunit; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.938
fadB
Fatty oxidation complex alpha subunit [includes: enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
 0.929
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.924
gabT
Similar to Escherichia coli 4-aminobutyrate aminotransferase GabT or b2662 SWALL:GABT_ECOLI (SWALL:P22256) (426 aa) fasta scores: E(): 1.7e-83, 53.6% id in 416 aa, and to Escherichia coli 4-aminobutyrate aminotransferase GoaG or b1302 SWALL:GOAG_ECOLI (SWALL:P50457) (421 aa) fasta scores: E(): 7e-115, 68.57% id in 420 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.921
fadA
3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
   
 0.908
atoB
Similar to Clostridium acetobutylicum acetyl-CoA acetyltransferase ThlA or Thl or cac2873 SWALL:THLA_CLOAB (SWALL:P45359) (392 aa) fasta scores: E(): 9.5e-81, 59.48% id in 390 aa, and to Escherichia coli acetyl-CoA acetyltransferase AtoB or b2224 SWALL:ATOB_ECOLI (SWALL:P76461) (394 aa) fasta scores: E(): 1.2e-87, 64.01% id in 389 aa; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.908
pflB
Similar to Escherichia coli formate acetyltransferase 1 PflB or Pfl or b0903 SWALL:PFLB_ECOLI (SWALL:P09373) (759 aa) fasta scores: E(): 0, 91.3% id in 759 aa.
  
 
 0.908
fadI
Putative 3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
   
 0.908
ECA0265
Putative zinc-binding oxidoreductase; Similar to Yersinia pestis probable zinc-binding dehydrogenase ypo3663 SWALL:Q8ZAW8 (EMBL:AJ414158) (325 aa) fasta scores: E(): 2.4e-87, 71.6% id in 324 aa.
   
 0.907
accC
Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
    
 0.905
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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