STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1474Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 hypothetical protein year or b1797 or z2839 or ecs2506 SWALL:YEAR_ECOLI (SWALL:P76248) (119 aa) fasta scores: E(): 3.1e-30, 66.66% id in 105 aa, and to Salmonella typhi hypothetical protein Sty1850 SWALL:Q8Z6D6 (EMBL:AL627271) (120 aa) fasta scores: E(): 5.8e-30, 65.71% id in 105 aa. (110 aa)    
Predicted Functional Partners:
ECA1472
Conserved hypothetical protein; Similar to Salmonella enterica subsp. enterica serovar Typhi Ty2 hypothetical protein T1150 t1150 SWALL:AAO68810 (EMBL:AE016838) (60 aa) fasta scores: E(): 2.6e-06, 52.72% id in 55 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yoag or b1796 or c2202 or z2838 or ecs2505 SWALL:YOAG_ECOLI (SWALL:P76247) (60 aa) fasta scores: E(): 7.9e-06, 49.09% id in 55 aa.
  
  
 0.870
ECA2743
Similar to Escherichia coli hypothetical protein yech or b1906 SWALL:YECH_ECOLI (SWALL:P46887) (79 aa) fasta scores: E(): 5.8e-18, 62.02% id in 79 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein yech or stm1936 or sty2144 SWALL:Q8XGI3 (EMBL:AE008786) (79 aa) fasta scores: E(): 1.1e-16, 59.49% id in 79 aa.
  
     0.711
norV
Anaerobic nitric oxide reductase flavorubredoxin; Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family.
 
    0.683
hmpX
Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.
  
  
 0.680
hybE
Hydrogenase-2 component protein; Similar to Escherichia coli, and Escherichia coli O6 hydrogenase-2 operon protein HybE or b2992 or c3729 SWALL:HYBE_ECOLI (SWALL:P37183) (162 aa) fasta scores: E(): 1.3e-27, 48.05% id in 154 aa.
 
    0.678
ytfE
Conserved hypothetical protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions.
   
  
 0.639
ECA1071
Conserved hypothetical protein; Similar to Escherichia coli O157:H7 orf, hypothetical protein z4045 or ecs3591 SWALL:Q8X7Z8 (EMBL:AE005501) (78 aa) fasta scores: E(): 7.7e-25, 81.33% id in 75 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein stm2923 or sty3048 SWALL:Q8XEM2 (EMBL:AE008833) (78 aa) fasta scores: E(): 2.1e-24, 78.66% id in 75 aa.
  
     0.637
ECA2415
Similar to Salmonella typhi hypothetical protein Sty2982 SWALL:Q8Z4B1 (EMBL:AL627276) (114 aa) fasta scores: E(): 6.2e-26, 58.92% id in 112 aa, and to Escherichia coli O6 hypothetical protein ygba or c3293 SWALL:AAN81742 (EMBL:AE016765) (114 aa) fasta scores: E(): 2.5e-25, 58.03% id in 112 aa.
  
   
 0.610
hybB
Similar to Escherichia coli probable Ni/Fe-hydrogenase 2 B-type cytochrome subunit hybb or b2995 SWALL:HYBB_ECOLI (SWALL:P37180) (392 aa) fasta scores: E(): 8.4e-123, 73.69% id in 384 aa.
  
     0.609
norW
Nitric oxide reductase FlrD-NAD(+) reductase; One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase.
 
    0.583
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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