Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
uhpCSimilar to Escherichia coli regulatory protein UhpC or b3667 SWALL:UHPC_ECOLI (SWALL:P09836) (439 aa) fasta scores: E(): 3.6e-99, 53.34% id in 433 aa, and to Yersinia pestis putative regulatory protein UhpC or ypo4007 SWALL:Q8ZA15 (EMBL:AJ414160) (443 aa) fasta scores: E(): 3.8e-103, 56.11% id in 417 aa. (441 aa)    
Predicted Functional Partners:
uhpB
Two-component system sensor histidine kinase; Similar to Escherichia coli sensor protein UhpB or b3668 SWALL:UHPB_ECOLI (SWALL:P09835) (500 aa) fasta scores: E(): 1e-25, 36.17% id in 528 aa, and to Vibrio cholerae sensor protein UhpB vca0683 SWALL:Q9KLQ9 (EMBL:AE004397) (527 aa) fasta scores: E(): 3.7e-66, 42.47% id in 518 aa.
 
 
  0.703
afuA
ABC transporter iron-binding protein; Similar to Actinobacillus pleuropneumoniae AfuA protein afuA SWALL:Q57512 (EMBL:U05042) (346 aa) fasta scores: E(): 1.4e-97, 69.56% id in 345 aa, and to Escherichia coli O157:H7 periplasmic ferric iron-binding protein AfuA or z0460 or ecs0415 SWALL:Q8X5J1 (EMBL:AE005215) (343 aa) fasta scores: E(): 4.2e-115, 84.01% id in 344 aa.
 
  
 0.701
uhpA
Two-component system response regulator protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri transcriptional regulatory protein UhpA or b3669 or c4593 or z5159 or ecs4606 or sf3792 SWALL:UHPA_ECOLI (SWALL:P10940) (196 aa) fasta scores: E(): 1.2e-29, 48.98% id in 196 aa.
     
 0.602
glpQ
Similar to Escherichia coli glycerophosphoryl diester phosphodiesterase, periplasmic precursor GlpQ or b2239 SWALL:GLPQ_ECOLI (SWALL:P09394) (358 aa) fasta scores: E(): 4e-103, 72.7% id in 359 aa.
 
  
 0.583
glpF
Glycerol uptake facilitator protein; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 glycerol uptake facilitator protein GlpF or b3927 or c4879 or z5472 or ecs4852 SWALL:GLPF_ECOLI (SWALL:P11244) (281 aa) fasta scores: E(): 4.4e-90, 80.71% id in 280 aa; Belongs to the MIP/aquaporin (TC 1.A.8) family.
 
  
 0.570
glpA
Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri anaerobic glycerol-3-phosphate dehydrogenase subunit A GlpA or b2241 or z3499 or ecs3126 or sf2323 SWALL:GLPA_ECOLI (SWALL:P13032) (542 aa) fasta scores: E(): 1.1e-153, 72.34% id in 546 aa; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.547
tyrP
Tyrosine-specific transport protein; Similar to Escherichia coli, and Shigella flexneri tyrosine-specific transport protein TyrP or b1907 or sf1953 SWALL:TYRP_ECOLI (SWALL:P18199) (403 aa) fasta scores: E(): 3.6e-112, 73.13% id in 402 aa.
  
     0.540
glpB
Anaerobic glycerol-3-phosphate dehydrogenase subunit B; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.
 
    0.492
afuB
Ferric ABC transporter permease protein; Similar to Actinobacillus pleuropneumoniae ferric transport system permease protein AfuB SWALL:AFUB_ACTPL (SWALL:Q44123) (687 aa) fasta scores: E(): 8.6e-167, 64.73% id in 672 aa, and to Escherichia coli O157:H7 putative permease component of transport system for ferric iron AfuB or z0459 or ecs0414 SWALL:Q8X5J2 (EMBL:AE005215) (692 aa) fasta scores: E(): 2.1e-217, 81.21% id in 692 aa.
 
     0.423
glpC
Similar to Escherichia coli, and Escherichia coli O157:H7 anaerobic glycerol-3-phosphate dehydrogenase subunit C GlpC or b2243 or z3501 or ecs3128 SWALL:GLPC_ECOLI (SWALL:P13034) (396 aa) fasta scores: E(): 2.2e-126, 76.82% id in 397 aa.
 
  
 0.423
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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