Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
uhpATwo-component system response regulator protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri transcriptional regulatory protein UhpA or b3669 or c4593 or z5159 or ecs4606 or sf3792 SWALL:UHPA_ECOLI (SWALL:P10940) (196 aa) fasta scores: E(): 1.2e-29, 48.98% id in 196 aa. (209 aa)    
Predicted Functional Partners:
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
 
 0.997
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
 
 0.966
hrpX
Two-component sensor kinase; Similar to Erwinia chrysanthemi HrpX SWALL:Q8KUM4 (EMBL:AF448202) (450 aa) fasta scores: E(): 3.4e-115, 68.25% id in 441 aa, and to Erwinia amylovora sensor kinase HrpX SWALL:Q9X3S8 (EMBL:AF083877) (494 aa) fasta scores: E(): 9.5e-100, 56.13% id in 481 aa.
 
 0.964
uhpB
Two-component system sensor histidine kinase; Similar to Escherichia coli sensor protein UhpB or b3668 SWALL:UHPB_ECOLI (SWALL:P09835) (500 aa) fasta scores: E(): 1e-25, 36.17% id in 528 aa, and to Vibrio cholerae sensor protein UhpB vca0683 SWALL:Q9KLQ9 (EMBL:AE004397) (527 aa) fasta scores: E(): 3.7e-66, 42.47% id in 518 aa.
 
 0.963
ECA3886
Putative membrane protein; Similar to the C-terminal region of many including Pseudomonas aeruginosa hypothetical protein Pa2870 SWALL:Q9HZX6 (EMBL:AE004713) (525 aa) fasta scores: E(): 1.9e-17, 39.39% id in 165 aa, and to Shewanella oneidensis ggdef domain protein so4457 SWALL:AAN57422 (EMBL:AE015878) (485 aa) fasta scores: E(): 2.1e-17, 39.03% id in 187 aa.
  
 0.953
narX
Nitrate/nitrite sensor kinase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri nitrate/nitrite sensor protein NarX or NarR or b1222 or z1998 or ecs1727 or sf1225 SWALL:NARX_ECOLI (SWALL:P10956) (598 aa) fasta scores: E(): 1.5e-115, 54.06% id in 603 aa.
 
 0.763
narQ
Similar to Escherichia coli nitrate/nitrite sensor protein NarQ or b2469 SWALL:NARQ_ECOLI (SWALL:P27896) (566 aa) fasta scores: E(): 3.6e-131, 64.45% id in 557 aa.
 
 0.757
evr
Virulence regulator; Similar to Pectobacterium carotovorum subsp. carotovorum virulence regulator Evr SWALL:AAN86997 (EMBL:AY167733) (204 aa) fasta scores: E(): 4.8e-39, 92.98% id in 114 aa. This CDS is truncated at the N-terminus relative to its orthologue in Pectobacterium carotovorum subsp. carotovorum.
  
     0.742
rcsD
Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
   
 0.636
uhpC
Similar to Escherichia coli regulatory protein UhpC or b3667 SWALL:UHPC_ECOLI (SWALL:P09836) (439 aa) fasta scores: E(): 3.6e-99, 53.34% id in 433 aa, and to Yersinia pestis putative regulatory protein UhpC or ypo4007 SWALL:Q8ZA15 (EMBL:AJ414160) (443 aa) fasta scores: E(): 3.8e-103, 56.11% id in 417 aa.
     
 0.602
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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