STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1514Putative permease; Similar to Yersinia pestis putative integral membrane protein y2365 SWALL:Q8D0D2 (EMBL:AE013839) (406 aa) fasta scores: E(): 5.3e-111, 83.06% id in 372 aa, and to Pasteurella multocida hypothetical protein Pm0449 SWALL:Q9CNI2 (EMBL:AE006080) (371 aa) fasta scores: E(): 1.3e-90, 67.92% id in 371 aa. (373 aa)    
Predicted Functional Partners:
ECA1515
ABC transporter ATP binding protein; Similar to Yersinia pestis similar to many ypo1946 or y2364 SWALL:AAM85922 (EMBL:AL031866) (237 aa) fasta scores: E(): 4.4e-66, 80.85% id in 235 aa, and to Pasteurella multocida hypothetical protein Pm0448 SWALL:Q9CNI3 (EMBL:AE006080) (227 aa) fasta scores: E(): 1.6e-59, 80% id in 220 aa.
 
 
 0.973
ECA1512
Putative membrane protein; Similar to Yersinia pestis putative integral membrane protein y2367 SWALL:AAM85925 (EMBL:AE013839) (484 aa) fasta scores: E(): 1.4e-119, 63.36% id in 464 aa, and to Pasteurella multocida hypothetical protein Pm0451 SWALL:Q9CNI0 (EMBL:AE006080) (465 aa) fasta scores: E(): 2e-85, 49.67% id in 463 aa.
 
  
 0.972
ECA1516
Similar to Yersinia pestis putative thioredoxin-family protein y2363 SWALL:AAM85921 (EMBL:AE013839) (176 aa) fasta scores: E(): 3.3e-34, 60.49% id in 162 aa, and to Pasteurella multocida ResA or pm0447 SWALL:Q9CNI4 (EMBL:AE006080) (175 aa) fasta scores: E(): 3e-18, 40% id in 165 aa.
 
     0.905
ECA1511
Putative exported protein; Similar to Yersinia pestis 102 kbases unstable region: from 1 to 119443 ypo1942 SWALL:Q9ZC52 (EMBL:AL031866) (175 aa) fasta scores: E(): 2.4e-63, 86.78% id in 174 aa, and to Pasteurella multocida hypothetical protein Pm0452 SWALL:Q9CNH9 (EMBL:AE006081) (173 aa) fasta scores: E(): 1.1e-57, 79.06% id in 172 aa.
    0.879
ECA1510
Putative iron permease; Similar to Yersinia pestis similarity to some hypothetical proteins in b. subtilis ypo1941 or y2370 SWALL:Q9ZC51 (EMBL:AL031866) (639 aa) fasta scores: E(): 5.2e-172, 74.02% id in 639 aa, and to Pasteurella multocida hypothetical protein Pm0453 pSWALL:Q9CNH8 (EMBL:AE006081) (634 aa) fasta scores: E(): 9.6e-146, 64.36% id in 623 aa.
 
    0.864
ECA1513
Putative permease; Similar to Yersinia pestis similar to ABC transporter: eg ybjz_ecoli hypothetical ABC transporter ypo1944 or y2366 SWALL:AAM85924 (EMBL:AL031866) (430 aa) fasta scores: E(): 9.9e-137, 81.86% id in 430 aa, and to Pasteurella multocida hypothetical protein Pm0450 SWALL:Q9CNI1 (EMBL:AE006080) (440 aa) fasta scores: E(): 4.2e-79, 67.95% id in 440 aa.
 
    
0.827
macB
Macrolide-specific ABC-type efflux carrier; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.811
ECA4128
Similar to Pseudomonas putida ABC transporter, ATP-binding protein, putative pp2317 SWALL:AAN67930 (EMBL:AE016782) (228 aa) fasta scores: E(): 5.5e-24, 42.85% id in 224 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical ABC transporter ATP-binding protein ybba or b0495 or z0648 or ecs0557 or sf0439 SWALL:AAN42094 (EMBL:AE000155) (228 aa) fasta scores: E(): 3.7e-24, 44.09% id in 220 aa.
 
 
 0.672
lolD
Lipoprotein releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
 
 
 0.651
lolA
Outer-membrane lipoproteins carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
 
 
 
 0.632
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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