STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1516Similar to Yersinia pestis putative thioredoxin-family protein y2363 SWALL:AAM85921 (EMBL:AE013839) (176 aa) fasta scores: E(): 3.3e-34, 60.49% id in 162 aa, and to Pasteurella multocida ResA or pm0447 SWALL:Q9CNI4 (EMBL:AE006080) (175 aa) fasta scores: E(): 3e-18, 40% id in 165 aa. (165 aa)    
Predicted Functional Partners:
ECA1512
Putative membrane protein; Similar to Yersinia pestis putative integral membrane protein y2367 SWALL:AAM85925 (EMBL:AE013839) (484 aa) fasta scores: E(): 1.4e-119, 63.36% id in 464 aa, and to Pasteurella multocida hypothetical protein Pm0451 SWALL:Q9CNI0 (EMBL:AE006080) (465 aa) fasta scores: E(): 2e-85, 49.67% id in 463 aa.
 
     0.937
ECA1513
Putative permease; Similar to Yersinia pestis similar to ABC transporter: eg ybjz_ecoli hypothetical ABC transporter ypo1944 or y2366 SWALL:AAM85924 (EMBL:AL031866) (430 aa) fasta scores: E(): 9.9e-137, 81.86% id in 430 aa, and to Pasteurella multocida hypothetical protein Pm0450 SWALL:Q9CNI1 (EMBL:AE006080) (440 aa) fasta scores: E(): 4.2e-79, 67.95% id in 440 aa.
 
     0.911
ECA1514
Putative permease; Similar to Yersinia pestis putative integral membrane protein y2365 SWALL:Q8D0D2 (EMBL:AE013839) (406 aa) fasta scores: E(): 5.3e-111, 83.06% id in 372 aa, and to Pasteurella multocida hypothetical protein Pm0449 SWALL:Q9CNI2 (EMBL:AE006080) (371 aa) fasta scores: E(): 1.3e-90, 67.92% id in 371 aa.
 
     0.904
ECA1515
ABC transporter ATP binding protein; Similar to Yersinia pestis similar to many ypo1946 or y2364 SWALL:AAM85922 (EMBL:AL031866) (237 aa) fasta scores: E(): 4.4e-66, 80.85% id in 235 aa, and to Pasteurella multocida hypothetical protein Pm0448 SWALL:Q9CNI3 (EMBL:AE006080) (227 aa) fasta scores: E(): 1.6e-59, 80% id in 220 aa.
   
 0.883
dsbD
Thiol:disulfide interchange protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
  
 
 0.861
ECA2649
Thioredoxin reductase.
  
 0.758
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.751
nrfE
Similar to Escherichia coli cytochrome C-type biogenesis protein NrfE or b4074 SWALL:NRFE_ECOLI (SWALL:P32710) (552 aa) fasta scores: E(): 4.4e-94, 57.73% id in 601 aa.
 
  
 0.746
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
    
 0.706
ccmF
Similar to Escherichia coli cytochrome C-type biogenesis protein CcmF or b2196 SWALL:CCMF_ECOLI (SWALL:P33927) (647 aa) fasta scores: E(): 1.2e-198, 74% id in 650 aa.
  
  
 0.705
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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