STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hasFSimilar to Pseudomonas fluorescens outer membrane protein HasF SWALL:Q9RHT0 (EMBL:AB023289) (442 aa) fasta scores: E(): 1.5e-85, 54.96% id in 433 aa, and to Erwinia chrysanthemi proteases secretion protein PrtF precursor prtF SWALL:PRTF_ERWCH (SWALL:P23598) (462 aa) fasta scores: E(): 2.1e-75, 48.82% id in 424 aa. Also similar to ECA2781 (48.956% identity in 431 aa overlap). (456 aa)    
Predicted Functional Partners:
hasE
HlyD family secretion protein; Similar to Pseudomonas fluorescens membrane fusion protein HasE SWALL:Q9RHT1 (EMBL:AB023289) (443 aa) fasta scores: E(): 2.5e-67, 52.28% id in 438 aa, and to Erwinia chrysanthemi proteases secretion protein PrtE SWALL:PRTE_ERWCH (SWALL:P23597) (448 aa) fasta scores: E(): 3.8e-62, 46.03% id in 441 aa. Also similar to ECA2782 (47.529% identity in 425 aa overlap).
 
 0.955
hasD
Type I secretion ATP-binding protein; Similar to Pseudomonas fluorescens ABC protein HasD SWALL:Q9RHT2 (EMBL:AB023289) (580 aa) fasta scores: E(): 2.6e-129, 65.58% id in 584 aa, and to Erwinia chrysanthemi proteases secretion ATP-binding protein PrtD SWALL:PRTD_ERWCH (SWALL:P23596) (575 aa) fasta scores: E(): 5.2e-113, 59.47% id in 570 aa. Also similar to ECA2783 (58.719% id. in 562 aa overlap).
 
  
 0.931
prtE
Similar to Erwinia chrysanthemi proteases secretion protein PrtE SWALL:PRTE_ERWCH (SWALL:P23597) (448 aa) fasta scores: E(): 9.7e-110, 72.33% id in 441 aa. Also similar to ECA1535 (47.529% in 425 aa overlap.
 
 0.838
macA
Similar to Escherichia coli macrolide-specific efflux protein MacA precursor MacA or b0878 SWALL:MACA_ECOLI (SWALL:P75830) (371 aa) fasta scores: E(): 8.9e-30, 37.17% id in 390 aa, and to Yersinia pestis putative HlyD family secretion protein ypo2999 or y1481 SWALL:AAM85052 (EMBL:AJ414154) (401 aa) fasta scores: E(): 3.8e-78, 64.69% id in 405 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.738
ECA2930
HlyD-family secretion protein; Similar to Pseudomonas putida RND efflux membrane fusion protein pp3301 SWALL:AAN68908 (EMBL:AE016786) (367 aa) fasta scores: E(): 2.8e-81, 70.1% id in 368 aa, and to Xylella fastidiosa component of multidrug efflux system xf2084 SWALL:Q9PBQ6 (EMBL:AE004023) (368 aa) fasta scores: E(): 3.9e-75, 63.95% id in 369 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.738
mdtA
Similar to Salmonella typhimurium putative HlyD family secretion protein stm2126 SWALL:Q8ZNQ3 (EMBL:AE008794) (413 aa) fasta scores: E(): 1.9e-84, 63.27% id in 403 aa, and to Salmonella typhi putative efflux system protein sty2339 SWALL:Q8Z5F8 (EMBL:AL627273) (413 aa) fasta scores: E(): 2.2e-84, 63.27% id in 403 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.738
ECA0801
Putative exported protein; Similar to Vibrio cholerae hypothetical protein vc0913 SWALL:Q9KTI9 (EMBL:AE004175) (352 aa) fasta scores: E(): 2.3e-10, 26.29% id in 232 aa, and to Shewanella oneidensis HlyD family secretion protein so3483 SWALL:AAN56476 (EMBL:AE015784) (369 aa) fasta scores: E(): 2.4e-09, 25.49% id in 251 aa. Note that there are no significant database matches to enterobacterial species; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.727
hasR
TonB-dependent heme receptor; Similar to Serratia marcescens HasR protein SWALL:P72473 (EMBL:Y08983) (899 aa) fasta scores: E(): 2.1e-176, 62.03% id in 893 aa, and to Yersinia pestis putative TonB dependent receptor protein ypo3923 or hasr or y0313 SWALL:Q8ZA89 (EMBL:AJ414159) (830 aa) fasta scores: E(): 1.5e-86, 52.03% id in 786 aa.
 
  
 0.727
prtW
Metalloprotease; Similar to Pectobacterium carotovorum subsp. carotovorum metalloprotease PrtW SWALL:Q9RB20 (EMBL:AF141295) (473 aa) fasta scores: E(): 4.7e-142, 84.51% id in 478 aa, and to Erwinia chrysanthemi secreted protease C precursor PrtC SWALL:PRTX_ERWCH (SWALL:P19144) (478 aa) fasta scores: E(): 5.8e-116, 66.03% id in 471 aa.
 
  
 0.692
emrA
Similar to Erwinia chrysanthemi EmrA protein EmrA SWALL:Q93KB1 (EMBL:AJ410307) (391 aa) fasta scores: E(): 7.9e-104, 72.63% id in 391 aa, and to Escherichia coli multidrug resistance protein A EmrA or b2685 SWALL:EMRA_ECOLI (SWALL:P27303) (390 aa) fasta scores: E(): 5.7e-94, 68.28% id in 391 aa.
  
 0.687
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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