STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1578Conserved hypothetical protein; Similar to Yersinia pestis nucleoprotein/polynucleotide-associated enzyme y2589 SWALL:AAM86144 (EMBL:AE013861) (179 aa) fasta scores: E(): 8.1e-50, 93.29% id in 179 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein stm4192 or sty4409 SWALL:Q8XF14 (EMBL:AE008896) (179 aa) fasta scores: E(): 3.5e-48, 88.26% id in 179 aa. (179 aa)    
Predicted Functional Partners:
ECA1224
Putative membrane protein; Similar to Yersinia pestis putative permease ypo3078 SWALL:Q8ZCB5 (EMBL:AJ414155) (809 aa) fasta scores: E(): 0, 75.24% id in 808 aa, and to Escherichia coli hypothetical protein ybbp or b0496 SWALL:YBBP_ECOLI (SWALL:P77504) (804 aa) fasta scores: E(): 0, 69.87% id in 810 aa.
 
     0.726
ECA3475
Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi hypothetical protein yajd or stm0411 or sty0449 or t2452 SWALL:YAJD_SALTY (SWALL:P40777) (115 aa) fasta scores: E(): 3.7e-46, 91.3% id in 115 aa, and to Yersinia pestis hypothetical protein Ypo1179 SWALL:Q8ZGU8 (EMBL:AJ414146) (113 aa) fasta scores: E(): 3.6e-45, 87.61% id in 113 aa.
  
     0.549
secM
Secretion monitor precursor; Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation. Belongs to the SecM family.
  
     0.544
ECA1579
Probable ketopantoate reductase; Similar to Escherichia coli, and Shigella flexneri 2-dehydropantoate 2-reductase PanE or ApbA or b0425 or sf0362 SWALL:PANE_ECOLI (SWALL:P77728) (303 aa) fasta scores: E(): 0.016, 24.29% id in 284 aa, and to Mycobacterium tuberculosis putative 2-dehydropantoate 2-reductase rv2573 or mt2649 or mtcy227.28C SWALL:PANE_MYCTU (SWALL:Q50648) (295 aa) fasta scores: E(): 5.3e-56, 51.2% id in 291 aa. Also similar to ECA1136 (24.101% id in 278 aa overlap).
       0.468
ECA2740
Similar to Yersinia pestis hypothetical protein ypo1269 or y2914 SWALL:AAM86465 (EMBL:AJ414147) (114 aa) fasta scores: E(): 5e-30, 63.15% id in 114 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical protein yejg or b2181 or c2718 or sf2268 SWALL:YEJG_ECOLI (SWALL:P33917) (114 aa) fasta scores: E(): 1.4e-27, 62.28% id in 114 aa.
  
     0.436
sulA
Cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
  
     0.424
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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