STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1579Probable ketopantoate reductase; Similar to Escherichia coli, and Shigella flexneri 2-dehydropantoate 2-reductase PanE or ApbA or b0425 or sf0362 SWALL:PANE_ECOLI (SWALL:P77728) (303 aa) fasta scores: E(): 0.016, 24.29% id in 284 aa, and to Mycobacterium tuberculosis putative 2-dehydropantoate 2-reductase rv2573 or mt2649 or mtcy227.28C SWALL:PANE_MYCTU (SWALL:Q50648) (295 aa) fasta scores: E(): 5.3e-56, 51.2% id in 291 aa. Also similar to ECA1136 (24.101% id in 278 aa overlap). (296 aa)    
Predicted Functional Partners:
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.923
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 0.923
panE
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
  
  0.916
alkB
Similar to Escherichia coli alkylated DNA repair protein AlkB or AidD or b2212 SWALL:ALKB_ECOLI (SWALL:P05050) (216 aa) fasta scores: E(): 6e-49, 56.94% id in 216 aa.
   
    0.557
ECA3093
Conserved hypothetical protein; Similar to Salmonella typhimurium molybdenum-binding periplasmic protein stm3141 SWALL:Q8ZM20 (EMBL:AE008844) (236 aa) fasta scores: E(): 1e-26, 40.25% id in 236 aa, and to Pasteurella multocida hypothetical protein Pm1146 SWALL:YB46_PASMU (SWALL:P57911) (241 aa) fasta scores: E(): 2e-26, 37.65% id in 239 aa.
  
     0.488
ECA1578
Conserved hypothetical protein; Similar to Yersinia pestis nucleoprotein/polynucleotide-associated enzyme y2589 SWALL:AAM86144 (EMBL:AE013861) (179 aa) fasta scores: E(): 8.1e-50, 93.29% id in 179 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein stm4192 or sty4409 SWALL:Q8XF14 (EMBL:AE008896) (179 aa) fasta scores: E(): 3.5e-48, 88.26% id in 179 aa.
       0.468
ECA0070
Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
  
     0.461
ECA3496
Similar to Yersinia pestis putative RpiR-family transcriptional regulatory protein ypo3259 or y0931 SWALL:Q8ZBX5 (EMBL:AJ414156) (281 aa) fasta scores: E(): 1.9e-75, 73.28% id in 277 aa, and to Rhizobium meliloti hypothetical protein r02078 r02078 or smc04363 SWALL:Q92NU4 (EMBL:AL591789) (280 aa) fasta scores: E(): 3e-21, 33.33% id in 273 aa.
  
     0.457
ECA1580
Putative cold-shock protein; Similar to Myxococcus xanthus CspB SWALL:Q9ZFK8 (EMBL:AF098529) (66 aa) fasta scores: E(): 0.057, 39.7% id in 68 aa, and to Yersinia pestis putative cold-shock protein y1165 SWALL:AAM84742 (EMBL:AE013720) (163 aa) fasta scores: E(): 2.6e-35, 66.24% id in 157 aa.
       0.449
ECA1404
Similar to Yersinia pestis hypothetical protein ypo1516 or y2652 SWALL:Q8ZG04 (EMBL:AJ414148) (418 aa) fasta scores: E(): 7e-158, 89.53% id in 411 aa, and to Bradyrhizobium japonicum Bll5694 protein bll5694 SWALL:BAC50959 (EMBL:AP005955) (441 aa) fasta scores: E(): 1e-80, 46.95% id in 411 aa.
  
     0.447
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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