STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1659Probable plasmid-related protein; Similar to Lactococcus lactis nicking enzyme SWALL:O87207 (EMBL:AE001272) (680 aa) fasta scores: E(): 2.9e-20, 33.77% id in 302 aa, and to Escherichia coli O6 hypothetical protein c2397 SWALL:AAN80856 (EMBL:AE016762) (500 aa) fasta scores: E(): 2.9e-119, 64.98% id in 477 aa, and to Thiobacillus ferrooxidans mobilization protein MobL mobL SWALL:MOBL_THIFE (SWALL:P20085) (378 aa) fasta scores: E(): 3.7e-09, 28.23% id in 294 aa. (486 aa)    
Predicted Functional Partners:
recB
Exodeoxyribonuclease V beta chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repai [...]
  
 
 0.773
recC
Exodeoxyribonuclease V gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repa [...]
  
 
 0.732
dltB
Peptidoglycan biosynthesis protein; Similar to Bacillus subtilis protein DltB or ipa-4R SWALL:DLTB_BACSU (SWALL:P39580) (395 aa) fasta scores: E(): 3.9e-24, 31% id in 400 aa, and to Staphylococcus epidermidis DltB membrane protein se0625 SWALL:AAO04222 (EMBL:AE016746) (404 aa) fasta scores: E(): 1.1e-23, 28.9% id in 346 aa; Belongs to the membrane-bound acyltransferase family.
  
    0.679
ECA2180
Hypothetical protein; No significant database matches.
 
 
 0.663
ECA3160
Similar to Salmonella typhimurium putative transcriptional regulator stm2195 SWALL:Q8ZNL4 (EMBL:AE008798) (129 aa) fasta scores: E(): 3.8e-14, 38.68% id in 137 aa, and to Salmonella typhi putative DNA-binding protein sty2429 SWALL:Q8Z5A0 (EMBL:AL627273) (129 aa) fasta scores: E(): 4.4e-14, 38.68% id in 137 aa.
  
    0.633
ECA2819
Hypothetical protein; Weakly similar to Bacillus subtilis hypothetical protein YsfE SWALL:P94533 (EMBL:Z75208) (80 aa) fasta scores: E(): 0.92, 30% id in 60 aa.
  
    0.629
ECA2977
Similar to Pseudomonas fluorescens hypothetical protein SWALL:AAN32872 (EMBL:AF461725) (79 aa) fasta scores: E(): 1.6e-14, 59.42% id in 69 aa, and to Bradyrhizobium japonicum Blr3308 protein blr3308 SWALL:BAC48573 (EMBL:AP005947) (105 aa) fasta scores: E(): 0.04, 31.34% id in 67 aa.
  
     0.541
dnaN
DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]
  
 
 0.506
dltA
Similar to Staphylococcus aureus D-alanine--poly(phosphoribitol) ligase subunit 1 DltA or mw0814 SWALL:DLTA_STAAW (SWALL:Q9S673) (485 aa) fasta scores: E(): 1.8e-42, 37.15% id in 471 aa, and to Lactococcus lactis D-alanine--poly(phosphoribitol) ligase subunit 1 DltA or ll1261 SWALL:DLTA_LACLA (SWALL:Q9CG49) (499 aa) fasta scores: E(): 1.3e-37, 32.03% id in 487 aa.
  
    0.489
nifL
Similar to Klebsiella pneumoniae nitrogen fixation regulatory protein NifL SWALL:NIFL_KLEPN (SWALL:P06772) (495 aa) fasta scores: E(): 2e-130, 66.46% id in 495 aa, and to Pantoea agglomerans NifL protein NifL SWALL:Q57340 (EMBL:X99694) (495 aa) fasta scores: E(): 5.8e-122, 61.21% id in 495 aa.
  
    0.471
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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