STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hns1DNA-binding protein Hns; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 DNA-binding protein H-NS SWALL:HNS_ECOLI (SWALL:P08936) (136 aa) fasta scores: E(): 3.4e-22, 61.19% id in 134 aa, and to Erwinia chrysanthemi Hns regulatory protein hnS SWALL:O53007 (EMBL:X89444) (135 aa) fasta scores: E(): 1.5e-22, 61.65% id in 133 aa. Also similar to ECA2893 (87.970% id in 133 aa overlap) and to ECA2328 (61.654% id in 133 aa overlap). (132 aa)    
Predicted Functional Partners:
hha
Haemolysin expression modulating protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri haemolysin expression modulating protein Hha or b0460 or c0578 or z0573 or ecs0513 or sf0405 SWALL:HHA_ECOLI (SWALL:P23870) (72 aa) fasta scores: E(): 1.1e-20, 77.61% id in 67 aa.
  
 
 0.775
ECA0304
Similar to Yersinia pestis putative membrane protein ypo3565 SWALL:AAM83730 (EMBL:AJ414157) (134 aa) fasta scores: E(): 1.5e-41, 87.97% id in 133 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein YhcB SWALL:YHCB_ECOLI (SWALL:P39436) (134 aa) fasta scores: E(): 5.6e-34, 80.31% id in 127 aa.
  
     0.727
zapB
Conserved hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.
  
    0.716
ompN
Similar to Escherichia coli outer membrane protein N precursor OmpN or b1377 SWALL:OMPN_ECOLI (SWALL:P77747) (377 aa) fasta scores: E(): 1.1e-76, 53.86% id in 388 aa.
  
  
 0.650
dsbA
Similar to Erwinia carotovora thiol:disulfide interchange protein DsbA precursor SWALL:DSBA_ERWCA (SWALL:Q9RB10) (207 aa) fasta scores: E(): 1.2e-76, 98.55% id in 207 aa.
  
   
 0.604
ftsN
Cell division protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
  
     0.590
holD
DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
     0.582
lpp
Major outer membrane lipoprotein; A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
  
    0.576
ECA1664
Putative lipoprotein; No significant database matches.
       0.558
ECA1666
Hypothetical protein; No significant database matches.
       0.545
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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