Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA1671Conserved hypothetical proteins; Similar to Yersinia pestis hypothetical y3270 SWALL:AAM86820 (EMBL:AE013928) (93 aa) fasta scores: E(): 1.2e-10, 46.57% id in 73 aa. (90 aa)    
Predicted Functional Partners:
kikA
Putative plasmid conjugation protein; Similar to Escherichia coli, and Salmonella typhimurium pkm101 conjugation proteins KikA SWALL:Q46691 (EMBL:U09868) (104 aa) fasta scores: E(): 5.5e-16, 49.47% id in 95 aa.
      
 0.466
citX
Similar to Escherichia coli, and Escherichia coli O157:H7 apo-citrate lyase phosphoribosyl-dephospho-CoA transferase citx or b0614 or z0758 or ecs0653 SWALL:CITX_ECOLI (SWALL:P77563) (183 aa) fasta scores: E(): 6.7e-24, 40.85% id in 164 aa.
      
 0.466
dhpS
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
      
 0.465
alpA
Similar to Escherichia coli prophage cp4-57 regulatory protein AlpA or Alp or b2624 SWALL:ALPA_ECOLI (SWALL:P33997) (70 aa) fasta scores: E(): 0.00017, 37.28% id in 59 aa, and to Yersinia pseudotuberculosis DNA-binding protein SWALL:Q9X9G5 (EMBL:AJ236887) (61 aa) fasta scores: E(): 4.7e-21, 86.88% id in 61 aa.
      
 0.465
hmpX
Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.
      
 0.464
mutL
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
      
 0.462
pagP
Putative antimicrobial peptide resistance and lipid A acylation protein; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.
      
 0.460
mgtE
Magnesium transporter; Acts as a magnesium transporter.
      
 0.460
acrR
Potential acrAB operon repressor; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri potential acrAB operon repressor AcrR or b0464 or c0582 or sf0409 SWALL:ACRR_ECOLI (SWALL:P34000) (215 aa) fasta scores: E(): 4.6e-49, 58.96% id in 212 aa.
      
 0.417
deoR
Deoxyribose operon repressor; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 deoxyribose operon repressor DeoR or NucR or b0840 or c0925 or z1067 or ecs0920 SWALL:DEOR_ECOLI (SWALL:P06217) (252 aa) fasta scores: E(): 6.5e-55, 54.72% id in 254 aa.
      
 0.415
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (22%) [HD]