STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
chpAPutative growth inhibitory protein; Similar to Escherichia coli, and Escherichia coli O157:H7 PemK-like protein 1 ChpA or MazF or ChpaK or b2782 or z4097 or ecs3642 SWALL:CHPA_ECOLI (SWALL:P33645) (111 aa) fasta scores: E(): 5.2e-31, 72.97% id in 111 aa, and to Deinococcus radiodurans ppgpp-regulated growth inhibitor chpa/mazf, putative dr0417 SWALL:Q9RX98 (EMBL:AE001901) (117 aa) fasta scores: E(): 5e-18, 48.21% id in 112 aa. (110 aa)    
Predicted Functional Partners:
chpR
Suppressor of growth inhibitory protein ChpA; Similar to Escherichia coli, and Escherichia coli O157:H7 PemI-like protein 1 ChpR or MazE or ChpaI or b2783 or z4098 or ecs3643 SWALL:CHPR_ECOLI (SWALL:P18534) (82 aa) fasta scores: E(): 4.6e-09, 38.55% id in 83 aa, and to Bacillus halodurans suppressor of ppgpp-regulated growth inhibitor bh3720 SWALL:Q9K6K9 (EMBL:AP001519) (81 aa) fasta scores: E(): 6.1e-05, 38.75% id in 80 aa.
 
 
 0.998
ECA1675
Putative integrase (partial); Partial CDS. Similar to the C-terminal regions of several phage integrases including Escherichia coli O6 putative P4-family integrase c2392 SWALL:AAN80851 (EMBL:AE016762) (406 aa) fasta scores: E(): 7.5e-08, 52.85% id in 70 aa, and to Xanthomonas axonopodis phage-related integrase IntA or xac1664 SWALL:Q8PLX5 (EMBL:AE011798) (396 aa) fasta scores: E(): 0.0014, 59.09% id in 44 aa.
       0.773
vagC
Plasmid-associated protein; Similar to Salmonella dublin virulence-associated protein VagC SWALL:VAGC_SALDU (SWALL:Q05459) (76 aa) fasta scores: E(): 3.8e-22, 77.63% id in 76 aa, and to Salmonella typhimurium Kor protein Kor SWALL:Q8L236 (EMBL:AP005147) (76 aa) fasta scores: E(): 6.3e-22, 76.31% id in 76 aa.
 
 
 0.708
insG
Transposase for insertion sequence element IS4 (partial); Similar to the N-terminal regions of several transposases including Escherichia coli transposase InsG for insertion sequence element IS4 InsG or b4278 SWALL:INSG_ECOLI (SWALL:P03835) (442 aa) fasta scores: E(): 1.6e-46, 74.32% id in 148 aa, and to Shigella flexneri IS4 orf s0243 SWALL:Q9AFL8 (EMBL:AF348706) (439 aa) fasta scores: E(): 1.6e-46, 74.32% id in 148 aa.
  
     0.672
ECA2195
Similar to the C-terminal regions of many including Escherichia coli transposase insg for insertion sequence element IS4 InsG or b4278 SWALL:INSG_ECOLI (SWALL:P03835) (442 aa) fasta scores: E(): 1.8e-36, 69.23% id in 143 aa.
  
     0.655
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
     
 0.628
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
      
 0.623
ECA0582
Putative plasmid-related protein; Similar to Escherichia coli PemK protein pemK SWALL:PEMK_ECOLI (SWALL:P13976) (133 aa) fasta scores: E(): 3e-07, 33.33% id in 111 aa, and to Plasmid R100 plasmid stable inheritance protein pemK SWALL:BAA78898 (EMBL:AP000342) (133 aa) fasta scores: E(): 3e-07, 33.33% id in 111 aa.
  
     0.619
parE
Topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
      
 0.587
mvpA
Putative plasmid protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
 
   
 0.584
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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