STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
chpRSuppressor of growth inhibitory protein ChpA; Similar to Escherichia coli, and Escherichia coli O157:H7 PemI-like protein 1 ChpR or MazE or ChpaI or b2783 or z4098 or ecs3643 SWALL:CHPR_ECOLI (SWALL:P18534) (82 aa) fasta scores: E(): 4.6e-09, 38.55% id in 83 aa, and to Bacillus halodurans suppressor of ppgpp-regulated growth inhibitor bh3720 SWALL:Q9K6K9 (EMBL:AP001519) (81 aa) fasta scores: E(): 6.1e-05, 38.75% id in 80 aa. (83 aa)    
Predicted Functional Partners:
chpA
Putative growth inhibitory protein; Similar to Escherichia coli, and Escherichia coli O157:H7 PemK-like protein 1 ChpA or MazF or ChpaK or b2782 or z4097 or ecs3642 SWALL:CHPA_ECOLI (SWALL:P33645) (111 aa) fasta scores: E(): 5.2e-31, 72.97% id in 111 aa, and to Deinococcus radiodurans ppgpp-regulated growth inhibitor chpa/mazf, putative dr0417 SWALL:Q9RX98 (EMBL:AE001901) (117 aa) fasta scores: E(): 5e-18, 48.21% id in 112 aa.
 
 
 0.999
ECA0582
Putative plasmid-related protein; Similar to Escherichia coli PemK protein pemK SWALL:PEMK_ECOLI (SWALL:P13976) (133 aa) fasta scores: E(): 3e-07, 33.33% id in 111 aa, and to Plasmid R100 plasmid stable inheritance protein pemK SWALL:BAA78898 (EMBL:AP000342) (133 aa) fasta scores: E(): 3e-07, 33.33% id in 111 aa.
 
 
 0.908
ECA1675
Putative integrase (partial); Partial CDS. Similar to the C-terminal regions of several phage integrases including Escherichia coli O6 putative P4-family integrase c2392 SWALL:AAN80851 (EMBL:AE016762) (406 aa) fasta scores: E(): 7.5e-08, 52.85% id in 70 aa, and to Xanthomonas axonopodis phage-related integrase IntA or xac1664 SWALL:Q8PLX5 (EMBL:AE011798) (396 aa) fasta scores: E(): 0.0014, 59.09% id in 44 aa.
       0.773
abrB
Putative membrane protein; Similar to Escherichia coli AbrB protein AbrB or b0715 SWALL:ABRB_ECOLI (SWALL:P75747) (348 aa) fasta scores: E(): 4.8e-66, 51.91% id in 339 aa, and to Salmonella typhi putative membrane protein sty0772 SWALL:Q8Z8D1 (EMBL:AL627268) (348 aa) fasta scores: E(): 2.1e-67, 53.39% id in 339 aa.
      
 0.625
birA
Bira bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
      
 0.530
doc
Similar to Bacteriophage P1 death on curing protein Doc SWALL:DOC_BPP1 (SWALL:Q06259) (126 aa) fasta scores: E(): 1.5e-05, 37.61% id in 109 aa, and to Escherichia coli Doc protein Doc SWALL:Q47172 (EMBL:X98141) (126 aa) fasta scores: E(): 1.1e-05, 37.61% id in 109 aa.
     
 0.530
ecnA
Entericidin A precursor; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 entericidin a precursor EcnA or b4147.1 or c5234 or z5753 or ecs5128.1 SWALL:ECNA_ECOLI (SWALL:P56548) (41 aa) fasta scores: E(): 4e-07, 58.14% id in 43 aa.
      
 0.530
mraZ
Conserved hypothetical protein; Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
      
 0.530
argR
Arginine repressor; Regulates arginine biosynthesis genes.
      
 0.506
insG
Transposase for insertion sequence element IS4 (partial); Similar to the N-terminal regions of several transposases including Escherichia coli transposase InsG for insertion sequence element IS4 InsG or b4278 SWALL:INSG_ECOLI (SWALL:P03835) (442 aa) fasta scores: E(): 1.6e-46, 74.32% id in 148 aa, and to Shigella flexneri IS4 orf s0243 SWALL:Q9AFL8 (EMBL:AF348706) (439 aa) fasta scores: E(): 1.6e-46, 74.32% id in 148 aa.
  
     0.502
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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