STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
intBPhage integrase; Similar to Yersinia pestis integrase IntB or ypo3438 SWALL:Q8ZBH6 (EMBL:AJ414157) (419 aa) fasta scores: E(): 2.4e-97, 58.15% id in 423 aa, and to Shigella flexneri integrase IntB or sf4224 SWALL:AAN45643 (EMBL:AE015430) (415 aa) fasta scores: E(): 2.4e-90, 58.45% id in 402 aa; Belongs to the 'phage' integrase family. (425 aa)    
Predicted Functional Partners:
ECA2754
Putative prophage primase; Similar to Escherichia coli O157:H7 alpha replication protein of prophage cp-933i z0339 or ecs0303 SWALL:Q8X7I5 (EMBL:AE005204) (796 aa) fasta scores: E(): 1.3e-10, 28.27% id in 633 aa, and to Pasteurella multocida hypothetical protein Pm1782 SWALL:Q9CK52 (EMBL:AE006215) (725 aa) fasta scores: E(): 9.7e-95, 45.25% id in 590 aa, and to Bacteriophage P4 DNA primase SWALL:Q8LTT9 (EMBL:AF509493) (362 aa) fasta scores: E(): 2.3e-41, 47.26% id in 347 aa.
 
     0.660
alpA
Similar to Escherichia coli prophage cp4-57 regulatory protein AlpA or Alp or b2624 SWALL:ALPA_ECOLI (SWALL:P33997) (70 aa) fasta scores: E(): 0.00017, 37.28% id in 59 aa, and to Yersinia pseudotuberculosis DNA-binding protein SWALL:Q9X9G5 (EMBL:AJ236887) (61 aa) fasta scores: E(): 4.7e-21, 86.88% id in 61 aa.
 
     0.629
xerC
Integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the t [...]
   
 
 0.598
xerD
Integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the b [...]
      
 0.544
ccmB
Heme exporter protein B; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
      
 0.544
uvrD
DNA helicase II; Similar to Escherichia coli DNA helicase II UvrD or MutU or PdeB or Rad or RecL or b3813 SWALL:UVRD_ECOLI (SWALL:P03018) (720 aa) fasta scores: E(): 0, 88.61% id in 720 aa.
   
  
 0.544
ECA2918
Putative phage-related protein; Similar to Bacteriophage P4 hypothetical 9.7 kDa protein SWALL:Y9K_BPP4 (SWALL:P12552) (88 aa) fasta scores: E(): 5.4e-05, 42.3% id in 52 aa, and to Yersinia pseudotuberculosis DNA-binding protein SWALL:Q9X9G5 (EMBL:AJ236887) (61 aa) fasta scores: E(): 1.5e-06, 45.45% id in 55 aa.
 
     0.484
parE
Topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
   
  
 0.474
ECA1678
Hypothetical protein; No significant database matches.
       0.447
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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