Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mtfAConserved hypothetical protein; Involved in the regulation of ptsG expression by binding and inactivating Mlc. (265 aa)    
Predicted Functional Partners:
ECA2258
Rok-family transcriptional regulator; Similar to Escherichia coli Mlc protein Mlc or b1594 SWALL:MLC_ECOLI (SWALL:P50456) (406 aa) fasta scores: E(): 1.3e-113, 71.92% id in 406 aa, and to Yersinia pestis putative rok family transcriptional regulatory protein mlc or ypo2268 SWALL:Q8ZEB4 (EMBL:AJ414151) (405 aa) fasta scores: E(): 7.4e-131, 81.72% id in 405 aa.
    
 
 0.735
ECA2388
Similar to Yersinia pestis putative membrane protein ypo1755 or y2554 SWALL:AAM86109 (EMBL:AJ414150) (153 aa) fasta scores: E(): 3e-41, 73.02% id in 152 aa, and to Escherichia coli, and Escherichia coli O6 hypothetical protein yobd or b1820 or c2227 SWALL:YOBD_ECOLI (SWALL:P76263) (152 aa) fasta scores: E(): 8.8e-33, 57.89% id in 152 aa.
  
     0.557
ECA1101
Similar to Salmonella typhimurium putative ABC-type multidrug/protein/lipid transport system, ATPase component YojI or stm2263 SWALL:Q8ZNH3 (EMBL:AE008801) (547 aa) fasta scores: E(): 9.8e-138, 70.09% id in 545 aa, and to Salmonella typhi putative ABC transporter ATP-binding protein sty2489 SWALL:Q8Z567 (EMBL:AL627274) (547 aa) fasta scores: E(): 1.6e-136, 69.54% id in 545 aa.
  
     0.515
ycgR
Conserved hypothetical protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
  
     0.507
queE
Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
     
 0.495
ECA2552
Similar to Yersinia pestis hypothetical protein Ypo1401 SWALL:Q8ZGA3 (EMBL:AJ414148) (297 aa) fasta scores: E(): 4.9e-98, 73.4% id in 297 aa, and to Salmonella typhimurium mukf protein stm0989 SWALL:Q8ZQB9 (EMBL:AE008742) (297 aa) fasta scores: E(): 2e-77, 58.78% id in 296 aa.
  
     0.491
flgM
Similar to Escherichia coli, and Shigella flexneri negative regulator of flagellin synthesis FlgM or b1071 or sf1077 SWALL:FLGM_ECOLI (SWALL:P43532) (97 aa) fasta scores: E(): 4.5e-14, 59.18% id in 98 aa.
  
     0.490
ECA0353
Similar to Yersinia pestis putative DedA-family membrane protein ypo0680 SWALL:Q8ZI36 (EMBL:AJ414144) (220 aa) fasta scores: E(): 1.6e-66, 75.11% id in 217 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein YghB SWALL:YGHB_ECOLI (SWALL:P33196) (219 aa) fasta scores: E(): 1e-60, 69.3% id in 215 aa.
  
  
 0.473
ECA0642
Similar to Yersinia pestis putative DedA-family membrane protein ypo0574 SWALL:Q8ZID1 (EMBL:AJ414143) (232 aa) fasta scores: E(): 1.2e-71, 77.29% id in 229 aa, and to Salmonella typhimurium putative DedA family, membrane protein stm3226 SWALL:Q8ZLX0 (EMBL:AE008848) (220 aa) fasta scores: E(): 2.8e-67, 76.27% id in 215 aa.
  
  
 0.473
dedA
Putative membrane protein; Similar to Escherichia coli, and Escherichia coli O157:H7 deda protein DedA or b2317 or z3579 or ecs3201 SWALL:DEDA_ECOLI (SWALL:P09548) (219 aa) fasta scores: E(): 2.8e-75, 86.11% id in 216 aa, and to Salmonella typhimurium, and Salmonella typhi putative DedA family protein or stm2367 or sty2598 SWALL:Q8XEL7 (EMBL:AE008806) (219 aa) fasta scores: E(): 1.5e-75, 86.11% id in 216 aa.
  
  
 0.473
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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