STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
flgMSimilar to Escherichia coli, and Shigella flexneri negative regulator of flagellin synthesis FlgM or b1071 or sf1077 SWALL:FLGM_ECOLI (SWALL:P43532) (97 aa) fasta scores: E(): 4.5e-14, 59.18% id in 98 aa. (98 aa)    
Predicted Functional Partners:
fliA
RNA polymerase sigma factor for flagellar operon; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
 
 0.997
flgN
Flagella synthesis protein; Similar to Salmonella typhimurium, and Salmonella typhi flagella synthesis protein FlgN or stm1171 or sty1210 SWALL:FLGN_SALTY (SWALL:P37406) (140 aa) fasta scores: E(): 2.4e-14, 38.88% id in 144 aa, and to Yersinia enterocolitica flagella synthesis protein FlgN SWALL:FLGN_YEREN (SWALL:Q56854) (147 aa) fasta scores: E(): 6.2e-22, 46.85% id in 143 aa.
 
  
 0.995
fliS
Flagellar protein; Similar to Salmonella typhimurium flagellar protein FliS or stm1961 SWALL:FLIS_SALTY (SWALL:P26609) (135 aa) fasta scores: E(): 1.4e-30, 69.85% id in 136 aa, and to Erwinia chrysanthemi FliS protein FliS SWALL:Q8RST3 (EMBL:AJ430202) (136 aa) fasta scores: E(): 4.4e-33, 73.52% id in 136 aa.
 
 
 0.966
fliL
Flagellar protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
 
  
 0.954
flgA
Flagella basal body P-ring formation protein; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.
 
  
 0.942
flgB
Flagellar basal-body rod protein; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
 
  
 0.936
flgK
Flagellar hook-associated protein 1; Similar to Salmonella typhimurium, and Salmonella typhi flagellar hook-associated protein 1 FlgK or FlaS or FlaW or stm1183 or sty1222 SWALL:FLGK_SALTY (SWALL:P15932) (552 aa) fasta scores: E(): 4.8e-81, 55.53% id in 569 aa.
 
  
 0.919
ycgR
Conserved hypothetical protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
 
  
 0.906
flgD
Basal-body rod modification protein; Required for flagellar hook formation. May act as a scaffolding protein.
 
  
 0.902
fliD
Flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
  
 0.895
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.