STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
fliTFlagellar protein; Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus. (126 aa)    
Predicted Functional Partners:
fliS
Flagellar protein; Similar to Salmonella typhimurium flagellar protein FliS or stm1961 SWALL:FLIS_SALTY (SWALL:P26609) (135 aa) fasta scores: E(): 1.4e-30, 69.85% id in 136 aa, and to Erwinia chrysanthemi FliS protein FliS SWALL:Q8RST3 (EMBL:AJ430202) (136 aa) fasta scores: E(): 4.4e-33, 73.52% id in 136 aa.
  
 
 0.983
fliD
Flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
 
 0.963
fliH
Similar to Salmonella typhimurium flagellar assembly protein FliH or Fla BIII or Fla AII.3 or stm1971 SWALL:FLIH_SALTY (SWALL:P15934) (235 aa) fasta scores: E(): 1.6e-43, 58.36% id in 245 aa.
  
  
 0.884
fliJ
Flagellar protein; Flagellar protein that affects chemotactic events. Belongs to the FliJ family.
  
 
 0.849
flhD
Flagellar transcriptional activator; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.
  
 
 
 0.829
fliO
Flagellar protein; Previously sequenced as Erwinia carotovora MopB protein mopB SWALL:MOPB_ERWCA (SWALL:P34199) (140 aa) fasta scores: E(): 2.5e-48, 95% id in 140 aa, and to Salmonella typhimurium, and Salmonella typhi flagellar protein flio flio or flbd or flap or stm1978 or sty2186 SWALL:FLIO_SALTY (SWALL:P54699) (125 aa) fasta scores: E(): 2.9e-14, 45% id in 120 aa.
  
  
 0.797
flgN
Flagella synthesis protein; Similar to Salmonella typhimurium, and Salmonella typhi flagella synthesis protein FlgN or stm1171 or sty1210 SWALL:FLGN_SALTY (SWALL:P37406) (140 aa) fasta scores: E(): 2.4e-14, 38.88% id in 144 aa, and to Yersinia enterocolitica flagella synthesis protein FlgN SWALL:FLGN_YEREN (SWALL:Q56854) (147 aa) fasta scores: E(): 6.2e-22, 46.85% id in 143 aa.
  
  
 0.773
fliK
Similar to Salmonella typhimurium flagellar hook-length control protein FliK or FlaE or FlaR or stm1974 SWALL:FLIK_SALTY (SWALL:P26416) (405 aa) fasta scores: E(): 1.9e-22, 35.3% id in 405 aa.
 
  
 0.767
fliN
Flagellar motor switch protein flin; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
  
  
 0.766
cheZ
Chemotaxis protein; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).
  
  
 0.764
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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