| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ECA1661 | bcsB | ECA1661 | ECA4372 | Hypothetical protein; No significant database matches. | Cellulose synthase catalytic subunit [UDP-forming] (pseudogene); Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family. | 0.529 |
| ECA1661 | betA | ECA1661 | ECA1746 | Hypothetical protein; No significant database matches. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.709 |
| ECA1661 | hmsH | ECA1661 | ECA4454 | Hypothetical protein; No significant database matches. | Putative hemin storage protein; Similar to Yersinia pestis HmsH or ypo1951 SWALL:Q56939 (EMBL:U22837) (822 aa) fasta scores: E(): 6e-141, 44% id in 825 aa. | 0.527 |
| ECA1661 | sseB | ECA1661 | ECA3229 | Hypothetical protein; No significant database matches. | Enhanced serine sensitivity protein; Similar to Escherichia coli, and Shigella flexneri protein SseB or b2522 or sf2569 SWALL:SSEB_ECOLI (SWALL:P31143) (258 aa) fasta scores: E(): 1.6e-51, 55.11% id in 254 aa. | 0.529 |
| aas | betA | ECA3641 | ECA1746 | Aas bifunctional protein [includes: 2-acylglycerophosphoethanolamine acyltransferase; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.820 |
| aas | pldA | ECA3641 | ECA4173 | Aas bifunctional protein [includes: 2-acylglycerophosphoethanolamine acyltransferase; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1. | Phospholipase A1; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. | 0.918 |
| aas | psd | ECA3641 | ECA3966 | Aas bifunctional protein [includes: 2-acylglycerophosphoethanolamine acyltransferase; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1. | Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.936 |
| bcsB | ECA1661 | ECA4372 | ECA1661 | Cellulose synthase catalytic subunit [UDP-forming] (pseudogene); Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family. | Hypothetical protein; No significant database matches. | 0.529 |
| bcsB | betA | ECA4372 | ECA1746 | Cellulose synthase catalytic subunit [UDP-forming] (pseudogene); Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.735 |
| betA | ECA1661 | ECA1746 | ECA1661 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Hypothetical protein; No significant database matches. | 0.709 |
| betA | aas | ECA1746 | ECA3641 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Aas bifunctional protein [includes: 2-acylglycerophosphoethanolamine acyltransferase; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1. | 0.820 |
| betA | bcsB | ECA1746 | ECA4372 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Cellulose synthase catalytic subunit [UDP-forming] (pseudogene); Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family. | 0.735 |
| betA | betB | ECA1746 | ECA1745 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.983 |
| betA | betI | ECA1746 | ECA1744 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | TetR-family transcriptional regulator; Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity). | 0.934 |
| betA | betT | ECA1746 | ECA1743 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | High-affinity choline transport protein; Similar to Escherichia coli, and Escherichia coli O157:H7 high-affinity choline transport protein BetT or b0314 or z0401 or ecs0360 SWALL:BETT_ECOLI (SWALL:P17447) (677 aa) fasta scores: E(): 0, 80.92% id in 671 aa; Belongs to the BCCT transporter (TC 2.A.15) family. | 0.777 |
| betA | hmsH | ECA1746 | ECA4454 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Putative hemin storage protein; Similar to Yersinia pestis HmsH or ypo1951 SWALL:Q56939 (EMBL:U22837) (822 aa) fasta scores: E(): 6e-141, 44% id in 825 aa. | 0.735 |
| betA | pldA | ECA1746 | ECA4173 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Phospholipase A1; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. | 0.826 |
| betA | psd | ECA1746 | ECA3966 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.805 |
| betA | sseB | ECA1746 | ECA3229 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Enhanced serine sensitivity protein; Similar to Escherichia coli, and Shigella flexneri protein SseB or b2522 or sf2569 SWALL:SSEB_ECOLI (SWALL:P31143) (258 aa) fasta scores: E(): 1.6e-51, 55.11% id in 254 aa. | 0.735 |
| betB | betA | ECA1745 | ECA1746 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.983 |