STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fabA3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (172 aa)    
Predicted Functional Partners:
fabI
Enoyl-[acyl-carrier-protein] reductase [NADH]; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri enoyl-[acyl-carrier-protein] reductase [NADH] FabI or EnvM or b1288 or z2512 or ecs1861 or sf1293 SWALL:FABI_ECOLI (SWALL:P29132) (261 aa) fasta scores: E(): 1.6e-84, 86.97% id in 261 aa.
  
 
 0.981
fabZ
(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
  
 
 0.966
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
  
 0.949
ECA3558
Short chain dehydrogenase; Similar to Photorhabdus luminescens Orf29 SWALL:AAO17195 (EMBL:AF346500) (248 aa) fasta scores: E(): 6e-74, 81.04% id in 248 aa, and to Escherichia coli hypothetical oxidoreductase ygff or b2902 SWALL:YGFF_ECOLI (SWALL:P52037) (247 aa) fasta scores: E(): 1.5e-55, 63.26% id in 245 aa.
  
 
 0.948
ECA3767
Similar to Pseudomonas aeruginosa probable short-chain dehydrogenase pa4162 SWALL:Q9HWL9 (EMBL:AE004832) (238 aa) fasta scores: E(): 8.7e-18, 39.58% id in 240 aa, and to Bradyrhizobium japonicum Blr3403 protein blr3403 SWALL:BAC48668 (EMBL:AP005947) (242 aa) fasta scores: E(): 4.5e-18, 35.19% id in 233 aa.
  
 
 0.948
ECA4492
Similar to Actinobacillus actinomycetemcomitans 3-oxoacyl-[acyl-carrier protein] reductase fabG SWALL:FABG_ACTAC (SWALL:P70720) (242 aa) fasta scores: E(): 1.5e-46, 56.19% id in 242 aa, and to Escherichia coli O6 3-oxoacyl-[acyl-carrier protein] reductase c1187 SWALL:Q8FJ14 (EMBL:AE016758) (243 aa) fasta scores: E(): 7.9e-68, 79.83% id in 243 aa.
  
 
 0.948
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 0.901
fabB
Similar to Escherichia coli, and Escherichia coli O6 3-oxoacyl-[acyl-carrier-protein] synthase I FabB or FabC or b2323 or c2869 SWALL:FABB_ECOLI (SWALL:P14926) (406 aa) fasta scores: E(): 1.3e-137, 92.32% id in 404 aa; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
 0.886
fabD
Similar to Escherichia coli, and Escherichia coli O6 malonyl CoA-acyl carrier protein transacylase FabD or TfpA or b1092 or c1361 SWALL:FABD_ECOLI (SWALL:P25715) (308 aa) fasta scores: E(): 1.7e-91, 78.82% id in 307 aa.
  
 
 0.800
accD
Acetyl-coenzyme A carboxylase carboxyl transferase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
 
 0.727
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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