STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sulACell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. (168 aa)    
Predicted Functional Partners:
ftsZ
Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 
 0.879
recN
DNA repair protein; May be involved in recombinational repair of damaged DNA.
   
  
 0.809
ECA4404
Similar to Yersinia pestis putative lipoprotein ypo4086 or y4103 SWALL:Q8Z9V4 (EMBL:AJ414160) (112 aa) fasta scores: E(): 2.8e-19, 55.35% id in 112 aa, and to Escherichia coli, and Shigella flexneri hypothetical protein yidq precursor yidq or b3688 or sf3775 SWALL:YIDQ_ECOLI (SWALL:P31454) (110 aa) fasta scores: E(): 1.2e-15, 46.55% id in 116 aa.
  
     0.701
secM
Secretion monitor precursor; Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation. Belongs to the SecM family.
  
     0.691
ECA0979
Putative exported protein; Similar to Salmonella typhimurium putative periplasmic protein yggn or stm3107 SWALL:Q8ZM42 (EMBL:AE008842) (239 aa) fasta scores: E(): 1.6e-48, 59.41% id in 239 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yggn or b2958 or c3544 or z4303 or ecs3834 SWALL:YGGN_ECOLI (SWALL:P46143) (239 aa) fasta scores: E(): 1.8e-48, 58.99% id in 239 aa.
  
     0.689
ECA4348
Similar to Yersinia pestis putative membrane protein ypo3816a or y0414 SWALL:Q8ZAI5 (EMBL:AJ414159) (90 aa) fasta scores: E(): 1.2e-22, 71.59% id in 88 aa, and to Shigella flexneri orf, conserved hypothetical protein yhhl or sf3484 SWALL:AAN44943 (EMBL:AE015356) (90 aa) fasta scores: E(): 5.6e-22, 69.41% id in 85 aa.
  
     0.687
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
  
 0.659
ECA3332
Similar to Yersinia pestis putative exported protein ypo3410 or y0776 SWALL:Q8ZBJ9 (EMBL:AJ414157) (115 aa) fasta scores: E(): 1.6e-30, 69.29% id in 114 aa, and to Escherichia coli, and Escherichia coli O6 hypothetical protein yacc precursor yacc or b0122 or c0151 SWALL:YACC_ECOLI (SWALL:P23838) (115 aa) fasta scores: E(): 1.6e-27, 64.34% id in 115 aa.
  
     0.659
ECA4351
Similar to Yersinia pestis putative membrane protein ypo3819 or y0411 SWALL:Q8ZAI2 (EMBL:AJ414159) (208 aa) fasta scores: E(): 7e-55, 66.98% id in 209 aa, and to Salmonella typhimurium, and Salmonella typhi putative inner membrane protein yhhn or stm3575 or sty4236 SWALL:Q8XH18 (EMBL:AE008864) (208 aa) fasta scores: E(): 5.2e-51, 63.63% id in 209 aa.
  
     0.636
ECA2528
Similar to Yersinia pestis hypothetical protein ypo2038 or y2274 SWALL:AAM85834 (EMBL:AJ414151) (186 aa) fasta scores: E(): 2.8e-45, 67.22% id in 180 aa, and to Escherichia coli hypothetical protein ycdy or b1035 SWALL:YCDY_ECOLI (SWALL:P75915) (184 aa) fasta scores: E(): 1.1e-41, 60.42% id in 187 aa.
  
     0.627
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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