STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (152 aa)    
Predicted Functional Partners:
ECA0350
Similar to Yersinia pestis putative iron-containing alcohol dehydrogenase ypo0678 SWALL:Q8ZI38 (EMBL:AJ414144) (385 aa) fasta scores: E(): 3.8e-112, 76.94% id in 386 aa, and to Escherichia coli hypothetical oxidoreductase YqhD SWALL:YQHD_ECOLI (SWALL:Q46856) (387 aa) fasta scores: E(): 3e-108, 73.64% id in 387 aa.
  
 
 0.912
gldA
Glycerol dehydrogenase; Similar to Escherichia coli, and Escherichia coli O6 glycerol dehydrogenase GldA or b3945 or c4904 SWALL:GLDA_ECOLI (SWALL:P32665) (367 aa) fasta scores: E(): 1.2e-57, 49.16% id in 358 aa.
     
 0.911
ECA1523
Putative glycerol dehydrogenase; Similar to Escherichia coli, and Escherichia coli O6 glycerol dehydrogenase GldA or b3945 or c4904 SWALL:GLDA_ECOLI (SWALL:P32665) (367 aa) fasta scores: E(): 3.2e-32, 36.26% id in 353 aa.
     
 0.911
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
 
    0.832
birA
Bira bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
  
 0.753
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
  
    0.680
pcnB
poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
  
 0.670
cca
tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
  
  
 0.670
ECA2839
Putative diacylglycerol kinase; Similar to Anabaena sp. hypothetical protein Alr2881 SWALL:Q8YT45 (EMBL:AP003591) (315 aa) fasta scores: E(): 1.9e-50, 48.43% id in 287 aa, and to Bacillus halodurans hypothetical protein Bh1953 SWALL:Q9KBH4 (EMBL:AP001513) (295 aa) fasta scores: E(): 2.6e-20, 29.55% id in 291 aa.
      0.640
osmE
Osmotically inducible lipoprotein E; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri osmotically inducible lipoprotein e precursor OsmE or Anr or b1739 or z2769 or ecs2445 or sf1487 SWALL:OSME_ECOLI (SWALL:P23933) (112 aa) fasta scores: E(): 2.6e-17, 49.54% id in 109 aa.
     
 0.546
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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