Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
acyPPutative acylphosphatase; Similar to Escherichia coli, and Escherichia coli O157:H7 putative acylphosphatase yccx or b0968 or z1320 or ecs1052 SWALL:ACYP_ECOLI (SWALL:P75877) (92 aa) fasta scores: E(): 4.4e-18, 61.95% id in 92 aa. (92 aa)    
Predicted Functional Partners:
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.962
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.954
aldB
Aldehyde dehydrogenase B; Similar to Escherichia coli aldehyde dehydrogenase B AldB or b3588 SWALL:ALDB_ECOLI (SWALL:P37685) (512 aa) fasta scores: E(): 1.4e-172, 83.2% id in 500 aa.
    
 0.945
maeB
Similar to Escherichia coli NADP-dependent malic enzyme MaeB or b2463 SWALL:MAO2_ECOLI (SWALL:P76558) (759 aa) fasta scores: E(): 0, 84.32% id in 759 aa.
    
 0.703
ECA3519
Putative acyl-CoA synthetase; Similar to Yersinia pestis putative acetyltransferase ypo3272 SWALL:Q8ZBW2 (EMBL:AJ414156) (880 aa) fasta scores: E(): 0, 79.56% id in 881 aa, and to Escherichia coli hypothetical protein yfiq or b2584 SWALL:YFIQ_ECOLI (SWALL:P76594) (886 aa) fasta scores: E(): 0, 76.84% id in 881 aa.
 
  
  0.689
calB
Similar to Pseudomonas sp. coniferyl aldehyde dehydrogenase CalB SWALL:CALB_PSESP (SWALL:O86447) (480 aa) fasta scores: E(): 1.4e-97, 55.5% id in 463 aa, and to Caulobacter crescentus probable coniferyl aldehyde dehydrogenase CalB or cc1849 SWALL:CALB_CAUCR (SWALL:Q9A777) (485 aa) fasta scores: E(): 2.5e-85, 50.96% id in 467 aa.
    
 0.499
hspQ
Conserved hypothetical protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family.
       0.488
adhE
Aldehyde-alcohol dehydrogenase; Similar to Escherichia coli, and Escherichia coli O157:H7 aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase, acetaldehyde dehydrogenase, and pyruvate-formate-lyase deactivase AdhE or Ana or b1241 or z2016 or ecs1741 SWALL:ADHE_ECOLI (SWALL:P17547) (890 aa) fasta scores: E(): 0, 89.1% id in 890 aa; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
    
 0.468
ECA0822
Putative carbon-nitrogen hydrolase; Similar to Escherichia coli O157:H7 hypothetical protein ybeM SWALL:YBEM_ECO57 (SWALL:P58054) (262 aa) fasta scores: E(): 4.7e-55, 53.25% id in 261 aa.
  
  
  0.453
nnrE
Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...]
 
     0.436
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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