STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1791Conserved hypothetical protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily. (197 aa)    
Predicted Functional Partners:
radC
DNA repair protein; Similar to Escherichia coli DNA repair protein RadC or b3638 SWALL:RADC_ECOLI (SWALL:P25531) (222 aa) fasta scores: E(): 1.1e-50, 58.14% id in 215 aa; Belongs to the UPF0758 family. YicR subfamily.
  
  
 0.587
ECA0593
Similar to Vibrio cholerae DNA repair protein RadC homolog SWALL:RADC_VIBCH (SWALL:Q9KVC9) (224 aa) fasta scores: E(): 2.2e-28, 55.47% id in 137 aa, and to Escherichia coli DNA repair protein RadC SWALL:RADC_ECOLI (SWALL:P25531) (222 aa) fasta scores: E(): 2.4e-26, 50.38% id in 129 aa; Belongs to the UPF0758 family.
  
  
 0.587
ECA1792
Similar to Yersinia pestis hypothetical protein ypo1594 or y1752 SWALL:Q8ZFU0 (EMBL:AJ414149) (174 aa) fasta scores: E(): 2.8e-56, 85.96% id in 171 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yced or g30k or b1088 or c1358 or z1727 or ecs1466 SWALL:YCED_ECOLI (SWALL:P14189) (173 aa) fasta scores: E(): 1e-53, 79.76% id in 173 aa.
       0.587
ECA2855
Conserved hypothetical protein; Similar to Shigella flexneri intergenic-region protein yees or sf2996 SWALL:AAN44477 (EMBL:AE015313) (163 aa) fasta scores: E(): 4.9e-27, 50.65% id in 152 aa, and to Escherichia coli intergenic-region protein SWALL:Q8VRA3 (EMBL:AF447814) (163 aa) fasta scores: E(): 5.7e-27, 50.65% id in 152 aa, and to Escherichia coli DNA repair protein RadC or b3638 SWALL:RADC_ECOLI (SWALL:P25531) (222 aa) fasta scores: E(): 5.6e-23, 47.51% id in 141 aa; Belongs to the UPF0758 family.
  
  
 0.587
rpmF
50S ribosomal protein L32; Similar to Escherichia coli, Escherichia coli O157:H7, Salmonella typhimurium, Salmonella typhi, and Shigella flexneri 50S ribosomal protein L32 RpmF or b1089 or z1728 or ecs1467 or stm1191 or sty1230 or sf1093 SWALL:RL32_ECOLI (SWALL:P02435) (56 aa) fasta scores: E(): 2.5e-18, 87.5% id in 56 aa; Belongs to the bacterial ribosomal protein bL32 family.
       0.562
plsX
Fatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
  
    0.531
fabD
Similar to Escherichia coli, and Escherichia coli O6 malonyl CoA-acyl carrier protein transacylase FabD or TfpA or b1092 or c1361 SWALL:FABD_ECOLI (SWALL:P25715) (308 aa) fasta scores: E(): 1.7e-91, 78.82% id in 307 aa.
     
 0.526
mreC
Rod shape-determining protein; Involved in formation and maintenance of cell shape.
  
  
 0.523
fabH
3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
     
 0.503
fabG
3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.440
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.