STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plsXFatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (348 aa)    
Predicted Functional Partners:
plsY
Putative membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
 
  
 0.984
rpmF
50S ribosomal protein L32; Similar to Escherichia coli, Escherichia coli O157:H7, Salmonella typhimurium, Salmonella typhi, and Shigella flexneri 50S ribosomal protein L32 RpmF or b1089 or z1728 or ecs1467 or stm1191 or sty1230 or sf1093 SWALL:RL32_ECOLI (SWALL:P02435) (56 aa) fasta scores: E(): 2.5e-18, 87.5% id in 56 aa; Belongs to the bacterial ribosomal protein bL32 family.
  
  
 0.958
fabD
Similar to Escherichia coli, and Escherichia coli O6 malonyl CoA-acyl carrier protein transacylase FabD or TfpA or b1092 or c1361 SWALL:FABD_ECOLI (SWALL:P25715) (308 aa) fasta scores: E(): 1.7e-91, 78.82% id in 307 aa.
  
  
 0.937
fabH
3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
  
 0.934
plsB
Glycerol-3-phosphate acyltransferase; Similar to Escherichia coli, and Escherichia coli O6 glycerol-3-phosphate acyltransferase PlsB or b4041 or c5011 SWALL:PLSB_ECOLI (SWALL:P00482) (806 aa) fasta scores: E(): 0, 77.08% id in 803 aa; Belongs to the GPAT/DAPAT family.
     
 0.930
ECA1792
Similar to Yersinia pestis hypothetical protein ypo1594 or y1752 SWALL:Q8ZFU0 (EMBL:AJ414149) (174 aa) fasta scores: E(): 2.8e-56, 85.96% id in 171 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yced or g30k or b1088 or c1358 or z1727 or ecs1466 SWALL:YCED_ECOLI (SWALL:P14189) (173 aa) fasta scores: E(): 1e-53, 79.76% id in 173 aa.
  
    0.831
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
    0.807
rpsM
30S ribosomal subunit protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.
   
    0.806
rpsH
30S ribosomal subunit protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
   
    0.803
rplO
50S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
    0.802
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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