STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mltGProbable aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (339 aa)    
Predicted Functional Partners:
ECA1804
Conserved hypothetical protein; Similar to Yersinia pestis putative deoxyribonuclease ypo1607 or y1766 SWALL:Q8ZFT0 (EMBL:AJ414149) (269 aa) fasta scores: E(): 1.2e-81, 75.47% id in 265 aa, and to Salmonella enterica subsp. enterica serovar Typhi Ty2 hypothetical protein T1718 t1718 SWALL:AAO69342 (EMBL:AE016839) (265 aa) fasta scores: E(): 5e-78, 74.14% id in 263 aa.
    
 0.925
holB
Similar to Escherichia coli DNA polymerase III, delta' subunit HolB or b1099 SWALL:HOLB_ECOLI (SWALL:P28631) (334 aa) fasta scores: E(): 1.2e-69, 54.71% id in 329 aa.
 
  
 0.897
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
  
 0.882
pabC
Similar to Escherichia coli 4-amino-4-deoxychorismate lyase PabC or b1096 SWALL:PABC_ECOLI (SWALL:P28305) (269 aa) fasta scores: E(): 7.2e-51, 53.96% id in 265 aa.
  
  
 0.875
mrcB
Penicillin-binding protein 1b; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
 
   
 0.652
mltD
Similar to Escherichia coli, and Escherichia coli O6 membrane-bound lytic murein transglycosylase D precursor MltD or DniR or b0211 or c0248 SWALL:MLTD_ECOLI (SWALL:P23931) (452 aa) fasta scores: E(): 7e-113, 66.81% id in 464 aa.
  
  
 0.606
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
    0.603
rlmL
Putative RNA methylase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.
  
    0.586
mrcA
Similar to Escherichia coli penicillin-binding protein 1A MrcA or PonA or b3396 SWALL:PBPA_ECOLI (SWALL:P02918) (850 aa) fasta scores: E(): 0, 77.9% id in 851 aa.
  
   
 0.571
ftsA
Cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
 
  
 0.570
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.