STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nagZBeta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (342 aa)    
Predicted Functional Partners:
anmK
Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
 
  
 0.802
ECA4161
Similar to Alteromonas sp. beta-hexosaminidase A precursor Cht60 SWALL:HEXA_ALTSO (SWALL:P48823) (598 aa) fasta scores: E(): 1.2e-60, 37.11% id in 590 aa, and to Ralstonia solanacearum putative hydrolase glycosidase protein rsc0769 or rs05085 SWALL:Q8Y1C1 (EMBL:AL646060) (734 aa) fasta scores: E(): 3.2e-82, 45.02% id in 653 aa.
  
  
 
0.756
ECA1814
Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi hypothetical protein ycfp or stm1210 or sty1250 SWALL:Q8XGQ0 (EMBL:AE008752) (180 aa) fasta scores: E(): 8.5e-62, 82.77% id in 180 aa, and to Yersinia pestis hypothetical protein ypo1616 or y1776 SWALL:AAM85344 (EMBL:AJ414149) (180 aa) fasta scores: E(): 3.8e-61, 81.11% id in 180 aa; Belongs to the UPF0227 family.
  
  
 0.722
bglX
Similar to Escherichia coli periplasmic beta-glucosidase precursor BglX or b2132 SWALL:BGLX_ECOLI (SWALL:P33363) (765 aa) fasta scores: E(): 3.4e-216, 73.3% id in 768 aa, and to Salmonella typhimurium periplasmic beta-glucosidase precursor BglX or stm2166 SWALL:BGLX_SALTY (SWALL:Q56078) (765 aa) fasta scores: E(): 3.9e-217, 73.17% id in 768 aa; Belongs to the glycosyl hydrolase 3 family.
  
  
 0.676
thiK
Conserved hypothetical protein; Catalyzes the phosphorylation of thiamine to thiamine phosphate.
  
    0.620
amiB
Similar to Escherichia coli N-acetylmuramoyl-L-alanine amidase AmiB precursor AmiB or b4169 SWALL:AMIB_ECOLI (SWALL:P26365) (445 aa) fasta scores: E(): 5.9e-74, 65.34% id in 430 aa.
    
 0.601
celV
Similar to Erwinia carotovora endoglucanase V precursor CelV SWALL:GUNV_ERWCA (SWALL:Q47096) (505 aa) fasta scores: E(): 9.2e-190, 94.65% id in 505 aa.
    
 0.596
mpl
udp-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.
  
   
 0.579
arbB
6-phospho-beta-glucosidase; Similar to Erwinia chrysanthemi 6-phospho-beta-glucosidase ArbB SWALL:ARBB_ERWCH (SWALL:P26206) (465 aa) fasta scores: E(): 2.3e-165, 80.56% id in 463 aa, and to Escherichia coli 6-phospho-beta-glucosidase BglB or b3721 SWALL:BGLB_ECOLI (SWALL:P11988) (470 aa) fasta scores: E(): 1.1e-149, 72.6% id in 460 aa; Belongs to the glycosyl hydrolase 1 family.
    
 0.567
bglA
6-phospho-beta-glucosidase; Similar to Escherichia coli 6-phospho-beta-glucosidase BglA or b2901 SWALL:BGLA_ECOLI (SWALL:Q46829) (479 aa) fasta scores: E(): 2.5e-159, 76.21% id in 475 aa, and to Bacillus subtilis 6-phospho-beta-glucosidase BglA SWALL:BGLA_BACSU (SWALL:P42973) (479 aa) fasta scores: E(): 3.2e-128, 62.18% id in 476 aa. Also similar to ECA1871 (ArbB) (53.669% id), ECA0662 (51.875% id), ECA4407 (32.500% id), ECA2166 (50.103% id), ECA4387 (49.899% id), ECA0859 (40.733% id), ECA1451 (39.754% id) and to ECA3646 (429.878% id); Belongs to the glycosyl hydrolase 1 family.
    
 0.552
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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