STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lolDLipoprotein releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (235 aa)    
Predicted Functional Partners:
lolC
Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 lipoprotein releasing system transmembrane protein LolC or b1116 or c1391 or z1757 or ecs1494 SWALL:LOLC_ECOLI (SWALL:P75956) (399 aa) fasta scores: E(): 1.7e-115, 79.75% id in 400 aa.
 
 0.991
lolE
Similar to Escherichia coli lipoprotein releasing system transmembrane protein LolE or b1118 SWALL:LOLE_ECOLI (SWALL:P75958) (413 aa) fasta scores: E(): 9.5e-123, 79.31% id in 411 aa.
 
 0.991
lolA
Outer-membrane lipoproteins carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
   
 
 0.757
macB
Macrolide-specific ABC-type efflux carrier; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
0.715
ECA1513
Putative permease; Similar to Yersinia pestis similar to ABC transporter: eg ybjz_ecoli hypothetical ABC transporter ypo1944 or y2366 SWALL:AAM85924 (EMBL:AL031866) (430 aa) fasta scores: E(): 9.9e-137, 81.86% id in 430 aa, and to Pasteurella multocida hypothetical protein Pm0450 SWALL:Q9CNI1 (EMBL:AE006080) (440 aa) fasta scores: E(): 4.2e-79, 67.95% id in 440 aa.
 
 
 0.674
rpsK
30S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
 
   
 0.665
ECA1514
Putative permease; Similar to Yersinia pestis putative integral membrane protein y2365 SWALL:Q8D0D2 (EMBL:AE013839) (406 aa) fasta scores: E(): 5.3e-111, 83.06% id in 372 aa, and to Pasteurella multocida hypothetical protein Pm0449 SWALL:Q9CNI2 (EMBL:AE006080) (371 aa) fasta scores: E(): 1.3e-90, 67.92% id in 371 aa.
 
 
 0.651
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
     
 0.603
ECA4127
Putative permease; Similar to Pseudomonas putida ABC efflux transporter, permease protein, putative pp0506 SWALL:AAN66134 (EMBL:AE016775) (421 aa) fasta scores: E(): 3.1e-13, 30.02% id in 423 aa, and to Vibrio cholerae hypothetical protein Vc2554 SWALL:Q9KP25 (EMBL:AE004324) (421 aa) fasta scores: E(): 2.7e-10, 27.86% id in 427 aa.
  
 
 0.601
gcp
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
    0.573
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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