Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ECA1831Putative methyltransferase; Similar to Haemophilus influenzae hypothetical protein Hi0095 SWALL:Y095_HAEIN (SWALL:Q57060) (251 aa) fasta scores: E(): 1e-51, 54.33% id in 254 aa, and to Pasteurella multocida hypothetical protein Pm1158 SWALL:Q9CLQ7 (EMBL:AE006156) (251 aa) fasta scores: E(): 1.9e-51, 53.54% id in 254 aa. (254 aa)    
Predicted Functional Partners:
ECA0705
Partial CDS. Similar to an internal region of Agrobacterium tumefaciens non-ribosomal peptide synthetase MtaD or atu3682 or agr_l_2311 SWALL:Q8U9P4 (EMBL:AE009297) (2399 aa) fasta scores: E(): 0.00074, 32.99% id in 97 aa, and to Anabaena sp. peptide synthetase all2648 SWALL:Q8YTR5 (EMBL:AP003590) (2588 aa) fasta scores: E(): 0.0032, 34.4% id in 93 aa.
    
 0.902
ECA1830
Similar to Methanosarcina mazei hypothetical protein Mm1422 SWALL:Q8PX00 (EMBL:AE013376) (107 aa) fasta scores: E(): 1.9e-13, 43.56% id in 101 aa, and to Fusobacterium nucleatum hypothetical cytosolic protein Fn1305 SWALL:Q8RE25 (EMBL:AE010636) (111 aa) fasta scores: E(): 6e-08, 35.92% id in 103 aa.
 
     0.848
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
 
 
 0.645
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 
 0.526
ECA0197
Similar to Yersinia pestis hypothetical protein ypo3780 SWALL:Q8ZAM0 (EMBL:AJ414158) (210 aa) fasta scores: E(): 1.8e-42, 56.65% id in 203 aa, and to Escherichia coli, and Shigella flexneri hypothetical protein YigP SWALL:YIGP_ECOLI (SWALL:P27852) (201 aa) fasta scores: E(): 1.2e-35, 48.78% id in 205 aa.
  
  
 0.508
ECA1829
Putative Crp/Fnr-family of transcriptional regulator; Similar to Pseudomonas aeruginosa transcriptional activator protein Anr or pa1544 SWALL:ANR_PSEAE (SWALL:P23926) (244 aa) fasta scores: E(): 2.9e-09, 25.59% id in 211 aa, and to Pseudomonas stutzeri DnrE protein DnrE SWALL:Q9X7J7 (EMBL:AJ131716) (231 aa) fasta scores: E(): 8.4e-10, 28% id in 175 aa.
       0.457
btuC
Vitamin B12 transport system permease; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.
       0.438
gcvP
Putative glycine cleavage system P protein (glycine dehydrogenase [decarboxylating]); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.409
ECA2694
Putative polyketide synthetase; Similar to Amycolatopsis mediterranei peptide synthetase BpsD SWALL:Q939Y2 (EMBL:Y16952) (581 aa) fasta scores: E(): 2e-44, 32.34% id in 575 aa, and to Myxococcus xanthus Ta1 SWALL:Q9Z5F4 (EMBL:AJ006977) (2393 aa) fasta scores: E(): 4e-51, 32.97% id in 552 aa.
    
 0.406
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.402
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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