STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (613 aa)    
Predicted Functional Partners:
eda
Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri Khg/kdpg aldolase [includes: 4-hydroxy-2-oxoglutarate aldolase and 2- dehydro-3-deoxyphosphogluconate aldolase Eda or Hga or KdgA or b1850 or c2263 or z2902 or ecs2560 or sf1860 SWALL:ALKH_ECOLI (SWALL:P10177) (213 aa) fasta scores: E(): 1.2e-67, 89.15% id in 212 aa, and to Erwinia chrysanthemi khg/kdpg aldolase [includes: 4-hydroxy-2-oxoglutarate aldolase Eda or KdgA SWALL:ALKH_ERWCH (SWALL:P38448) (213 aa) fasta scores: E(): 7e-67, 89.2% id in 213 aa.
 
 
 0.988
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
  
 0.959
gntV
Gluconokinase; Similar to Escherichia coli thermosensitive gluconokinase IdnK or GntV or b4268 SWALL:IDNK_ECOLI (SWALL:P39208) (187 aa) fasta scores: E(): 5.8e-34, 62.02% id in 158 aa.
  
 
 0.925
gnd
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
   
 0.924
kdgK
2-dehydro-3-deoxygluconokinase; Similar to Erwinia chrysanthemi 2-dehydro-3-deoxygluconokinase KdgK SWALL:KDGK_ERWCH (SWALL:P45416) (310 aa) fasta scores: E(): 1.4e-100, 82.25% id in 310 aa.
 
  
 0.920
pgl
Conserved hypothetical protein; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate.
     
 0.900
ECA3507
Putative exported protein; Similar to Bradyrhizobium japonicum Blr0368 protein Blr0368 SWALL:BAC45633 (EMBL:AP005936) (398 aa) fasta scores: E(): 5.2e-15, 43.73% id in 359 aa, and to Yersinia pestis hypothetical protein ypo1149 or y3033 SWALL:Q8ZGX4 (EMBL:AJ414146) (334 aa) fasta scores: E(): 3.3e-12, 36.31% id in 347 aa.
     
  0.900
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
  
  
 0.811
glk
Glucokinase; Similar to Escherichia coli, and Escherichia coli O157:H7 glucokinase Glk or b2388 or z3654 or ecs3268 SWALL:GLK_ECOLI (SWALL:P46880) (321 aa) fasta scores: E(): 7.3e-98, 76.32% id in 321 aa; Belongs to the bacterial glucokinase family.
 
  
 0.778
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
 
  
 0.766
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.