STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sufSSelenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. (407 aa)    
Predicted Functional Partners:
sufC
Similar to Escherichia coli probable ATP-dependent transporter SufC or b1682 SWALL:SUFC_ECOLI (SWALL:P77499) (248 aa) fasta scores: E(): 2.7e-71, 85.08% id in 248 aa, and to Erwinia chrysanthemi SufC protein SufC SWALL:Q9EXP4 (EMBL:AJ301654) (248 aa) fasta scores: E(): 6.7e-72, 85.88% id in 248 aa.
 
  
 0.985
sufD
Conserved hypothetical protein; Similar to Escherichia coli SufD protein SufD or b1681 SWALL:SUFD_ECOLI (SWALL:P77689) (423 aa) fasta scores: E(): 1e-99, 61.5% id in 413 aa, and to Erwinia chrysanthemi SufD protein sSufD SWALL:Q9EXP3 (EMBL:AJ301654) (430 aa) fasta scores: E(): 1.6e-114, 69.78% id in 417 aa.
 
 
 0.981
sufE
Conserved hypothetical protein; Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L- alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process; Belongs to the SufE family.
 
 0.973
sufB
Conserved hypothetical protein; Similar to Erwinia chrysanthemi SufB protein SufB SWALL:Q9EXP5 (EMBL:AJ301654) (499 aa) fasta scores: E(): 1.6e-185, 88.6% id in 500 aa, and to Escherichia coli sufb protein SufB or b1683 SWALL:SUFB_ECOLI (SWALL:P77522) (495 aa) fasta scores: E(): 2.1e-176, 84.4% id in 500 aa.
 
 
 0.963
ECA2649
Thioredoxin reductase.
 
 
 0.928
metB
Similar to Escherichia coli cystathionine gamma-synthase MetB or b3939 SWALL:METB_ECOLI (SWALL:P00935) (386 aa) fasta scores: E(): 3.8e-129, 87.01% id in 385 aa.
     
 0.902
icsU
NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 0.899
ECA1011
Putative Fe-S metabolism associated protein; Similar to Yersinia pestis hypothetical protein ypo1027 or y3157 SWALL:AAM86707 (EMBL:AJ414146) (147 aa) fasta scores: E(): 1.3e-34, 64.28% id in 140 aa, and to Escherichia coli, and Escherichia coli O157:H7 hypothetical protein ygdk or b2811 or z4128 or ecs3671 SWALL:YGDK_ECOLI (SWALL:Q46926) (147 aa) fasta scores: E(): 2.4e-31, 60.27% id in 146 aa.
 
 0.885
nifU
Nitrogen fixation protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
 
 0.807
nifQ
Nitrogen fixation protein; Similar to Pantoea agglomerans NifQ protein NifQ SWALL:Q52074 (EMBL:X99694) (171 aa) fasta scores: E(): 1.7e-37, 59.64% id in 171 aa, and to Klebsiella pneumoniae NifQ protein NifQ SWALL:NIFQ_KLEPN (SWALL:P10392) (167 aa) fasta scores: E(): 1.8e-33, 58.08% id in 167 aa.
  
 
 0.805
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.