STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
sufEConserved hypothetical protein; Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L- alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process; Belongs to the SufE family. (138 aa)    
Predicted Functional Partners:
sufS
Selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo.
 0.984
sufD
Conserved hypothetical protein; Similar to Escherichia coli SufD protein SufD or b1681 SWALL:SUFD_ECOLI (SWALL:P77689) (423 aa) fasta scores: E(): 1e-99, 61.5% id in 413 aa, and to Erwinia chrysanthemi SufD protein sSufD SWALL:Q9EXP3 (EMBL:AJ301654) (430 aa) fasta scores: E(): 1.6e-114, 69.78% id in 417 aa.
 
 
 0.936
sufC
Similar to Escherichia coli probable ATP-dependent transporter SufC or b1682 SWALL:SUFC_ECOLI (SWALL:P77499) (248 aa) fasta scores: E(): 2.7e-71, 85.08% id in 248 aa, and to Erwinia chrysanthemi SufC protein SufC SWALL:Q9EXP4 (EMBL:AJ301654) (248 aa) fasta scores: E(): 6.7e-72, 85.88% id in 248 aa.
 
 
 0.927
sufB
Conserved hypothetical protein; Similar to Erwinia chrysanthemi SufB protein SufB SWALL:Q9EXP5 (EMBL:AJ301654) (499 aa) fasta scores: E(): 1.6e-185, 88.6% id in 500 aa, and to Escherichia coli sufb protein SufB or b1683 SWALL:SUFB_ECOLI (SWALL:P77522) (495 aa) fasta scores: E(): 2.1e-176, 84.4% id in 500 aa.
 
 
 0.915
csdA
Similar to Escherichia coli cysteine sulfinate desulfinase CsdA or b2810 SWALL:CSDA_ECOLI (SWALL:Q46925) (401 aa) fasta scores: E(): 1.6e-104, 69.82% id in 401 aa, and to Salmonella typhimurium putative selenocysteine lyase csda or stm2984 SWALL:Q8ZMC3 (EMBL:AE008836) (401 aa) fasta scores: E(): 3.2e-101, 67.83% id in 401 aa.
 0.889
sufA
Conserved hypothetical protein; Similar to Erwinia chrysanthemi SufA protein SufA SWALL:Q9EXP6 (EMBL:AJ301654) (123 aa) fasta scores: E(): 2.9e-33, 68.29% id in 123 aa, and to Escherichia coli SufA protein SufA or b1684 SWALL:SUFA_ECOLI (SWALL:P77667) (122 aa) fasta scores: E(): 3e-30, 67.52% id in 117 aa; Belongs to the HesB/IscA family.
  
  
 0.573
chpR
Suppressor of growth inhibitory protein ChpA; Similar to Escherichia coli, and Escherichia coli O157:H7 PemI-like protein 1 ChpR or MazE or ChpaI or b2783 or z4098 or ecs3643 SWALL:CHPR_ECOLI (SWALL:P18534) (82 aa) fasta scores: E(): 4.6e-09, 38.55% id in 83 aa, and to Bacillus halodurans suppressor of ppgpp-regulated growth inhibitor bh3720 SWALL:Q9K6K9 (EMBL:AP001519) (81 aa) fasta scores: E(): 6.1e-05, 38.75% id in 80 aa.
  
    0.466
ECA1865
Similar to Yersinia pestis hypothetical protein y1940 SWALL:AAM85506 (EMBL:AE013797) (354 aa) fasta scores: E(): 4.6e-90, 72.64% id in 340 aa, and to Shigella flexneri orf, conserved hypothetical protein ycfs or sf1117 SWALL:AAN42735 (EMBL:AE015138) (321 aa) fasta scores: E(): 2.7e-68, 62.98% id in 308 aa.
       0.402
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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