STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccmCHeme exporter protein C; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (246 aa)    
Predicted Functional Partners:
ccmB
Heme exporter protein B; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
 0.998
ccmA
Heme exporter protein A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 
 0.996
ccmE
Cytochrome C-type biogenesis protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
 
 0.996
ccmD
Heme exporter protein D; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
 
 
 0.985
dsbE
Thiol:disulfide interchange protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri thiol:disulfide interchange protein DsbE or CcmG or b2195 or z3452 or ecs3084 or sf2279 SWALL:DSBE_ECOLI (SWALL:P33926) (185 aa) fasta scores: E(): 5.4e-57, 77.47% id in 182 aa.
 
  
 0.978
ccmF
Similar to Escherichia coli cytochrome C-type biogenesis protein CcmF or b2196 SWALL:CCMF_ECOLI (SWALL:P33927) (647 aa) fasta scores: E(): 1.2e-198, 74% id in 650 aa.
 
  
 0.975
ccmH1
Cytochrome C-type biogenesis protein; Possible subunit of a heme lyase.
 
   
 0.967
ccmH2
Cytochrome C-type biogenesis protein; Similar to the C-terminal half of Escherichia coli, and Shigella flexneri cytochrome C-type biogenesis protein CcmH precursor CcmH or b2194 or sf2278 SWALL:CCMH_ECOLI (SWALL:P33925) (350 aa) fasta scores: E(): 5.9e-35, 48.14% id in 216 aa.
 
  
 0.925
nrfE
Similar to Escherichia coli cytochrome C-type biogenesis protein NrfE or b4074 SWALL:NRFE_ECOLI (SWALL:P32710) (552 aa) fasta scores: E(): 4.4e-94, 57.73% id in 601 aa.
 
  
 0.921
nrfF
Formate-dependent nitrite reductase complex subunit; Possible subunit of a heme lyase.
 
  
 0.921
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.