Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ECA1906Putative hydrolase; Similar to Clostridium perfringens hypothetical protein Cpe0723 cpe0723 SWALL:Q8XMG6 (EMBL:AP003187) (262 aa) fasta scores: E(): 2.4e-24, 33.07% id in 260 aa, and to Vibrio vulnificus predicted hydrolase of the had superfamily vv21429 SWALL:AAO08308 (EMBL:AE016813) (267 aa) fasta scores: E(): 2.1e-23, 31.67% id in 262 aa. (263 aa)    
Predicted Functional Partners:
ribD
Riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 0.629
ECA4180
Putative hydrolase; Similar to Escherichia coli, and Shigella flexneri hypothetical protein yigb or b3812 or sf3890 SWALL:YIGB_ECOLI (SWALL:P23306) (238 aa) fasta scores: E(): 1.4e-60, 66.8% id in 238 aa, and to Yersinia pestis putative haloacid dehalogenase-like hydrolase ypo3842 or y0388 SWALL:Q8ZAG0 (EMBL:AJ414159) (238 aa) fasta scores: E(): 3.4e-60, 66.38% id in 238 aa.
    
 0.617
ribF
Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri riboflavin biosynthesis protein ribf [includes: riboflavin kinase; FMN adenylyltransferase] RibF or b0025 or c0029 or z0029 or ecs0028 or sf0021 SWALL:RIBF_ECOLI (SWALL:P08391) (313 aa) fasta scores: E(): 2.3e-89, 76.03% id in 313 aa.
   
 0.587
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
     
 0.569
fre
NAD(P)H-flavin reductase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 NAD(P)H-flavin reductase Fre or FlrD or FadI or FsrC or UbiB or b3844 or c4791 or z5365 or ecs4772 SWALL:FRE_ECOLI (SWALL:P23486) (232 aa) fasta scores: E(): 5.8e-71, 75.86% id in 232 aa.
   
 
  0.548
ECA2224
Putative transporter; Similar to Salmonella typhimurium putative transport protein stm0868 SWALL:Q8ZQK6 (EMBL:AE008736) (403 aa) fasta scores: E(): 1.8e-64, 46.83% id in 395 aa, and to Escherichia coli hypothetical protein ybjj ybjj or b0845 SWALL:YBJJ_ECOLI (SWALL:P75810) (402 aa) fasta scores: E(): 9.3e-64, 46.26% id in 402 aa.
 
    0.541
ECA1923
Riboflavin synthase alpha chain; Similar to Escherichia coli, and Shigella flexneri riboflavin synthase alpha chain RibE or RibC or b1662 or sf1690 SWALL:RISA_ECOLI (SWALL:P29015) (213 aa) fasta scores: E(): 7e-61, 76.84% id in 203 aa.
     
  0.540
hpaC
Similar to Escherichia coli 4-hydroxyphenylacetate 3-monooxygenase, reductase component HpaC SWALL:HPAC_ECOLI (SWALL:Q57501) (170 aa) fasta scores: E(): 1.8e-19, 41.66% id in 156 aa, and to Escherichia coli putative flavin:NADH reductase ycdh or b1007 SWALL:YCDH_ECOLI (SWALL:P75893) (164 aa) fasta scores: E(): 5e-35, 60.37% id in 159 aa; EC number 1.6.8.-.
     
  0.540
ECA0860
Similar to Bacillus subtilis PTS system, beta-glucoside-specific IIabc component BglP or N17C SWALL:PTBA_BACSU (SWALL:P40739) (609 aa) fasta scores: E(): 1.1e-61, 39.06% id in 640 aa, and to Escherichia coli PTS system, arbutin-, cellobiose-, and salicin-specific IIabc component ascf or b2715 SWALL:PTDA_ECOLI (SWALL:P24241) (485 aa) fasta scores: E(): 6.6e-58, 38.55% id in 472 aa.
 
  
 0.495
nagE
Similar to Escherichia coli PTS system, N-acetylglucosamine-specific IIABC component NagE or pPstN or b0679 SWALL:PTAA_ECOLI (SWALL:P09323) (648 aa) fasta scores: E(): 7.8e-62, 45.16% id in 496 aa.
  
 
 0.430
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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