STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1921L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (517 aa)    
Predicted Functional Partners:
ECA1919
Similar to Escherichia coli putative electron transport protein ykgf or b0307 SWALL:YKGF_ECOLI (SWALL:P77536) (475 aa) fasta scores: E(): 1.4e-163, 85.83% id in 473 aa, and to Shigella flexneri orf, conserved hypothetical protein ykgf or sf0259 SWALL:AAN41919 (EMBL:AE015061) (475 aa) fasta scores: E(): 1.7e-163, 85.83% id in 473 aa.
 
  
 0.939
ECA1918
Similar to Shigella flexneri orf, conserved hypothetical protein ykgg or sf0258 SWALL:AAN41918 (EMBL:AE015061) (231 aa) fasta scores: E(): 4.1e-59, 66.23% id in 231 aa, and to Escherichia coli hypothetical protein ykgg or b0308 SWALL:YKGG_ECOLI (SWALL:P77433) (231 aa) fasta scores: E(): 1.3e-58, 65.8% id in 231 aa.
 
  
 0.890
lctD
L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
  
  
 0.877
ECA1920
Similar to Escherichia coli hypothetical protein ykge or b0306 SWALL:YKGE_ECOLI (SWALL:P77252) (239 aa) fasta scores: E(): 3.5e-78, 79.49% id in 239 aa, and to Shigella flexneri putative dehydrogenase subunit ykge or sf0260 SWALL:AAN41920 (EMBL:AE015061) (239 aa) fasta scores: E(): 1.7e-78, 80.33% id in 239 aa.
 
  
 0.874
ECA1856
Putative FAD-binding oxidase; Similar to Yersinia pestis hypothetical protein ypo2407 or y1932 SWALL:AAM85498 (EMBL:AJ414152) (1018 aa) fasta scores: E(): 0, 82.41% id in 1018 aa, and to Escherichia coli hypothetical protein ydij or b1687 SWALL:YDIJ_ECOLI (SWALL:P77748) (1018 aa) fasta scores: E(): 0, 79.05% id in 1017 aa.
 
  
 0.798
glpC
Similar to Escherichia coli, and Escherichia coli O157:H7 anaerobic glycerol-3-phosphate dehydrogenase subunit C GlpC or b2243 or z3501 or ecs3128 SWALL:GLPC_ECOLI (SWALL:P13034) (396 aa) fasta scores: E(): 2.2e-126, 76.82% id in 397 aa.
 
  
 0.650
pdhR
Pyruvate dehydrogenase complex repressor; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 pyruvate dehydrogenase complex repressor PdhR or GenA or AceC or b0113 or c0140 or z0123 or ecs0117 SWALL:PDHR_ECOLI (SWALL:P06957) (254 aa) fasta scores: E(): 2.9e-77, 82.28% id in 254 aa.
 
  
 0.622
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
  
 0.619
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
  
 0.565
adhE
Aldehyde-alcohol dehydrogenase; Similar to Escherichia coli, and Escherichia coli O157:H7 aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase, acetaldehyde dehydrogenase, and pyruvate-formate-lyase deactivase AdhE or Ana or b1241 or z2016 or ecs1741 SWALL:ADHE_ECOLI (SWALL:P17547) (890 aa) fasta scores: E(): 0, 89.1% id in 890 aa; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
   
  
 0.470
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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