STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1923Riboflavin synthase alpha chain; Similar to Escherichia coli, and Shigella flexneri riboflavin synthase alpha chain RibE or RibC or b1662 or sf1690 SWALL:RISA_ECOLI (SWALL:P29015) (213 aa) fasta scores: E(): 7e-61, 76.84% id in 203 aa. (211 aa)    
Predicted Functional Partners:
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
 
 0.998
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
  
 0.997
ribD
Riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
 0.997
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
 
 0.996
ribF
Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri riboflavin biosynthesis protein ribf [includes: riboflavin kinase; FMN adenylyltransferase] RibF or b0025 or c0029 or z0029 or ecs0028 or sf0021 SWALL:RIBF_ECOLI (SWALL:P08391) (313 aa) fasta scores: E(): 2.3e-89, 76.03% id in 313 aa.
  
 
 0.939
ECA4180
Putative hydrolase; Similar to Escherichia coli, and Shigella flexneri hypothetical protein yigb or b3812 or sf3890 SWALL:YIGB_ECOLI (SWALL:P23306) (238 aa) fasta scores: E(): 1.4e-60, 66.8% id in 238 aa, and to Yersinia pestis putative haloacid dehalogenase-like hydrolase ypo3842 or y0388 SWALL:Q8ZAG0 (EMBL:AJ414159) (238 aa) fasta scores: E(): 3.4e-60, 66.38% id in 238 aa.
   
 
 0.903
fre
NAD(P)H-flavin reductase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 NAD(P)H-flavin reductase Fre or FlrD or FadI or FsrC or UbiB or b3844 or c4791 or z5365 or ecs4772 SWALL:FRE_ECOLI (SWALL:P23486) (232 aa) fasta scores: E(): 5.8e-71, 75.86% id in 232 aa.
    
  0.902
ECA4198
Putative exported phosphatase; Similar to Pseudomonas syringae phytase PhyM SWALL:AAN77879 (EMBL:AY156083) (428 aa) fasta scores: E(): 3.4e-77, 48.73% id in 433 aa, and to Escherichia coli glucose-1-phosphatase precursor Agp or b1002 SWALL:AGP_ECOLI (SWALL:P19926) (413 aa) fasta scores: E(): 1.5e-31, 31.08% id in 415 aa.
     
  0.900
hisI
Similar to Escherichia coli histidine biosynthesis bifunctional protein HisIE [includes: phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase HisI or hisie or b2026 SWALL:HIS2_ECOLI (SWALL:P06989) (203 aa) fasta scores: E(): 2e-64, 80.09% id in 201 aa; In the N-terminal section; belongs to the PRA-CH family.
  
    0.722
rpmJ2
Similar to Salmonella typhimurium, and Salmonella typhi 50S ribosomal protein L36 2 rpmj2 or stm0470 or sty0513 SWALL:R362_SALTY (SWALL:Q8XF38) (46 aa) fasta scores: E(): 6.8e-14, 71.73% id in 46 aa; Belongs to the bacterial ribosomal protein bL36 family.
   
    0.619
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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