Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cfaSimilar to Escherichia coli, and Escherichia coli O6 cyclopropane-fatty-acyl-phospholipid synthase Cfa or CdfA or b1661 or c2055 SWALL:CFA_ECOLI (SWALL:P30010) (381 aa) fasta scores: E(): 2.7e-113, 68.75% id in 368 aa. (383 aa)    
Predicted Functional Partners:
ECA2214
Putative amine oxidoreductase; Similar to Vibrio cholerae hypothetical protein Vc1120 SWALL:Q9KSY6 (EMBL:AE004192) (426 aa) fasta scores: E(): 7.9e-99, 58.33% id in 420 aa, and to Shewanella oneidensis conserved hypothetical protein so3381 SWALL:AAN56379 (EMBL:AE015774) (416 aa) fasta scores: E(): 9.4e-90, 56.25% id in 416 aa.
  
 0.965
ECA2213
Similar to Vibrio vulnificus conserved hypothetical protein vv12933 SWALL:AAO11265 (EMBL:AE016806) (255 aa) fasta scores: E(): 8.4e-49, 49.37% id in 241 aa, and to Pseudomonas putida conserved hypothetical protein pp2735 SWALL:AAN68343 (EMBL:AE016784) (269 aa) fasta scores: E(): 8.5e-32, 41.39% id in 244 aa.
  
 0.806
ECA0705
Partial CDS. Similar to an internal region of Agrobacterium tumefaciens non-ribosomal peptide synthetase MtaD or atu3682 or agr_l_2311 SWALL:Q8U9P4 (EMBL:AE009297) (2399 aa) fasta scores: E(): 0.00074, 32.99% id in 97 aa, and to Anabaena sp. peptide synthetase all2648 SWALL:Q8YTR5 (EMBL:AP003590) (2588 aa) fasta scores: E(): 0.0032, 34.4% id in 93 aa.
     
 0.696
ECA2692
Similar to Agrobacterium tumefaciens amine oxidase, flavin-containing atu1977 or agr_c_3599 SWALL:Q8UDY9 (EMBL:AE009150) (457 aa) fasta scores: E(): 3.3e-25, 27.16% id in 438 aa, and to Rhizobium loti hypothetical protein Mll8087 SWALL:Q984A4 (EMBL:AP003013) (448 aa) fasta scores: E(): 4.9e-26, 29.45% id in 421 aa.
  
 0.696
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
  
  
 0.663
gcvP
Putative glycine cleavage system P protein (glycine dehydrogenase [decarboxylating]); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
  0.626
ECA2348
Conserved hypothetical protein; Similar to Salmonella typhimurium putative ser protein kinase yeag or stm1285 SWALL:Q8ZPW2 (EMBL:AE008755) (644 aa) fasta scores: E(): 0, 94.09% id in 644 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yeag or b1783 or c2188 or z2823 or ecs2492 SWALL:YEAG_ECOLI (SWALL:P77391) (644 aa) fasta scores: E(): 0, 94.09% id in 644 aa.
   
    0.413
purR
Purine nucleotide synthesis repressor; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
       0.404
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (14%) [HD]