| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cfa | purR | ECA1924 | ECA1925 | Similar to Escherichia coli, and Escherichia coli O6 cyclopropane-fatty-acyl-phospholipid synthase Cfa or CdfA or b1661 or c2055 SWALL:CFA_ECOLI (SWALL:P30010) (381 aa) fasta scores: E(): 2.7e-113, 68.75% id in 368 aa. | Purine nucleotide synthesis repressor; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.404 |
| gltB | purR | ECA0312 | ECA1925 | Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa. | Purine nucleotide synthesis repressor; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.592 |
| proY | purR | ECA1115 | ECA1925 | Similar to Salmonella typhimurium proline-specific permease ProY or stm0400 SWALL:PROY_SALTY (SWALL:P37460) (456 aa) fasta scores: E(): 7.4e-145, 82.78% id in 453 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 proline-specific permease ProY or b0402 or c0512 or z0500 or ecs0452 SWALL:PROY_ECOLI (SWALL:P77327) (457 aa) fasta scores: E(): 4.3e-145, 82.56% id in 453 aa. | Purine nucleotide synthesis repressor; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.544 |
| purR | cfa | ECA1925 | ECA1924 | Purine nucleotide synthesis repressor; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | Similar to Escherichia coli, and Escherichia coli O6 cyclopropane-fatty-acyl-phospholipid synthase Cfa or CdfA or b1661 or c2055 SWALL:CFA_ECOLI (SWALL:P30010) (381 aa) fasta scores: E(): 2.7e-113, 68.75% id in 368 aa. | 0.404 |
| purR | gltB | ECA1925 | ECA0312 | Purine nucleotide synthesis repressor; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa. | 0.592 |
| purR | proY | ECA1925 | ECA1115 | Purine nucleotide synthesis repressor; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | Similar to Salmonella typhimurium proline-specific permease ProY or stm0400 SWALL:PROY_SALTY (SWALL:P37460) (456 aa) fasta scores: E(): 7.4e-145, 82.78% id in 453 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 proline-specific permease ProY or b0402 or c0512 or z0500 or ecs0452 SWALL:PROY_ECOLI (SWALL:P77327) (457 aa) fasta scores: E(): 4.3e-145, 82.56% id in 453 aa. | 0.544 |