STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA1927Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri protein ydhd or b1654 or c2048 or z2676 or ecs2363 or sf1682 SWALL:YDHD_ECOLI (SWALL:P37010) (115 aa) fasta scores: E(): 5e-40, 88.79% id in 116 aa, and to Salmonella typhimurium, and Salmonella typhi putative glutaredoxin protein ydhd or stm1433 or sty1689 SWALL:Q8XGR7 (EMBL:AE008762) (115 aa) fasta scores: E(): 1.5e-40, 90.51% id in 116 aa; Belongs to the glutaredoxin family. Monothiol subfamily. (116 aa)    
Predicted Functional Partners:
bolA
Morphogene, putative regulator of murein genes; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri BolA or b0435 or c0548 or sf0379 SWALL:BOLA_ECOLI (SWALL:P15298) (105 aa) fasta scores: E(): 4.6e-28, 71.28% id in 101 aa, and to Salmonella typhimurium, and Salmonella typhi morphogene, putative regulator of murein genes bola or stm0446 or sty0488 SWALL:Q8XFC2 (EMBL:AE008716) (105 aa) fasta scores: E(): 5.4e-28, 70.29% id in 101 aa; Belongs to the BolA/IbaG family.
 
 
 0.904
nfuA
Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 0.823
visB
Similar to Escherichia coli 2-octaprenyl-6-methoxyphenol hydroxylase UbiH or VisB or b2907 SWALL:UBIH_ECOLI (SWALL:P25534) (392 aa) fasta scores: E(): 2.4e-96, 62.24% id in 392 aa.
  
    0.695
ECA0300
Similar to Yersinia pestis bolA-like protein ypo3570 SWALL:AAM83735 (EMBL:AJ414157) (87 aa) fasta scores: E(): 9.3e-29, 88.09% id in 84 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri protein YrbA SWALL:YRBA_ECOLI (SWALL:P43781) (84 aa) fasta scores: E(): 2.9e-27, 84.52% id in 84 aa; Belongs to the BolA/IbaG family.
 
 
 
 0.665
visC
Putative monooxygenase; Similar to Escherichia coli protein VisC or b2906 SWALL:VISC_ECOLI (SWALL:P25535) (400 aa) fasta scores: E(): 3.8e-114, 72.43% id in 399 aa.
  
    0.625
erpA
Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG.
 
 0.625
ubiF
Similar to Escherichia coli 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase UbiF or b0662 SWALL:UBIF_ECOLI (SWALL:P75728) (391 aa) fasta scores: E(): 4.8e-94, 65.7% id in 382 aa.
  
    0.574
gloB
Probable hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
  
  
 0.551
ubiG
3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
  
 
   0.546
gshB
Similar to Escherichia coli glutathione synthetase GshB or Gsh-II or b2947 SWALL:GSHB_ECOLI (SWALL:P04425) (316 aa) fasta scores: E(): 2.1e-100, 81.2% id in 314 aa; Belongs to the prokaryotic GSH synthase family.
  
     0.546
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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