STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
horGlobal regulator; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family. (145 aa)    
Predicted Functional Partners:
hfq
Putative phage-related protein (host factor-I protein); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
   
  
 0.630
expI
Similar to Erwinia carotovora autoinducer synthesis protein CarI or HslI SWALL:CARI_ERWCA (SWALL:P33880) (216 aa) fasta scores: E(): 1.1e-85, 97.22% id in 216 aa, and to Erwinia carotovora autoinducer synthesis protein ExpI SWALL:EXPI_ERWCA (SWALL:P33882) (217 aa) fasta scores: E(): 9.2e-65, 72.94% id in 207 aa, and to Erwinia chrysanthemi AhlI SWALL:Q8KUJ8 (EMBL:AF448800) (212 aa) fasta scores: E(): 6.5e-54, 62.26% id in 212 aa.
  
   
 0.586
fis
DNA-binding protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.
      
 0.558
pepN
Similar to Escherichia coli aminopeptidase N PepN or b0932 SWALL:AMPN_ECOLI (SWALL:P04825) (869 aa) fasta scores: E(): 0, 75.66% id in 867 aa.
      
 0.520
csrA
Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). Belongs to the CsrA/RsmA family.
   
  
 0.516
phoU
Phosphate transport system protein; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.
   
  
 0.507
ptsG
PTS system, glucose-specific IIBC component; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 PTS system, glucose-specific IIBC component PtsG or GlcA or Umg or b1101 or c1373 or z1740 or ecs1479 SWALL:PTGB_ECOLI (SWALL:P05053) (477 aa) fasta scores: E(): 7.7e-159, 87.42% id in 477 aa.
      
 0.500
ihfA
Integration host factor alpha-subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
   
    0.493
ugd
Similar to Escherichia coli UDP-glucose 6-dehydrogenase Ugd or b2028 SWALL:UDG_ECOLI (SWALL:P76373) (388 aa) fasta scores: E(): 2.4e-110, 73.96% id in 388 aa, and to Vibrio cholerae nucleotide sugar dehydrogenase SWALL:Q56625 (EMBL:U47057) (388 aa) fasta scores: E(): 1e-110, 72.93% id in 388 aa.
      
 0.490
pehR
Two-component response regulator of virulence determinants; Similar to Pectobacterium carotovorum subsp. carotovorum response regulator PehR SWALL:Q9ZIN9 (EMBL:AF022772) (227 aa) fasta scores: E(): 1.5e-76, 91.26% id in 229 aa, and to Erwinia chrysanthemi PhoP protein phoP SWALL:CAD33237 (EMBL:AJ489252) (222 aa) fasta scores: E(): 7.2e-74, 87.83% id in 222 aa.
   
  
 0.483
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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