STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
anmKConserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (370 aa)    
Predicted Functional Partners:
murQ
Putative phophosugar-binding protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
  
 0.981
nagZ
Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
 
  
 0.771
ECA4161
Similar to Alteromonas sp. beta-hexosaminidase A precursor Cht60 SWALL:HEXA_ALTSO (SWALL:P48823) (598 aa) fasta scores: E(): 1.2e-60, 37.11% id in 590 aa, and to Ralstonia solanacearum putative hydrolase glycosidase protein rsc0769 or rs05085 SWALL:Q8Y1C1 (EMBL:AL646060) (734 aa) fasta scores: E(): 3.2e-82, 45.02% id in 653 aa.
 
  
 0.739
ECA1934
Similar to Yersinia pestis putative lipoprotein ypo2371 SWALL:Q8ZE18 (EMBL:AJ414152) (104 aa) fasta scores: E(): 1.1e-16, 53.33% id in 105 aa, and to Yersinia enterocolitica hypothetical protein SWALL:YOR4_YEREN (SWALL:P28837) (101 aa) fasta scores: E(): 2.1e-15, 51.54% id in 97 aa.
       0.555
ECA2483
Putative peptidase; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical metalloprotease yeba precursor yeba or b1856 or c2270 or sf1866 SWALL:YEBA_ECOLI (SWALL:P24204) (440 aa) fasta scores: E(): 6.7e-128, 75.11% id in 442 aa, and to Salmonella typhimurium putative peptidase yeba or stm1890 SWALL:Q8ZNV9 (EMBL:AE008784) (439 aa) fasta scores: E(): 5.8e-128, 75.05% id in 441 aa.
 
    0.505
ribD
Riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.478
ampG
Beta-lactamase induction signal transducer; Similar to Escherichia coli, and Escherichia coli O157:H7 ampg protein AmpG or b0433 or z0536 or ecs0487 SWALL:AMPG_ECOLI (SWALL:P36670) (491 aa) fasta scores: E(): 3.7e-141, 70.9% id in 488 aa.
  
   
 0.453
nagA
N-acetylglucosamine-6-phosphate deacetylase; Similar to Escherichia coli, and Escherichia coli O157:H7 N-acetylglucosamine-6-phosphate deacetylase NagA or b0677 or z0824 or ecs0707 SWALL:NAGA_ECOLI (SWALL:P15300) (382 aa) fasta scores: E(): 1.7e-109, 72.55% id in 379 aa.
 
   
 0.423
mltG
Probable aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
     
 0.412
nagB
Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
     
 0.408
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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