Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
pgpBPhosphatidylglycerophosphatase B; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri phosphatidylglycerophosphatase B PgpB or b1278 or z2529 or ecs1851 or sf1282 SWALL:PGPB_ECOLI (SWALL:P18201) (254 aa) fasta scores: E(): 6.1e-68, 61.75% id in 251 aa. (258 aa)    
Predicted Functional Partners:
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
 
 0.976
cls
Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
    
 0.973
ECA3261
Similar to Yersinia pestis putative membrane protein ypo2924 SWALL:Q8ZCP9 (EMBL:AJ414154) (215 aa) fasta scores: E(): 1.7e-62, 74.27% id in 206 aa, and to Salmonella typhimurium putatative phosphoserine phosphatase yfhb or stm2569 SWALL:Q8ZN27 (EMBL:AE008817) (211 aa) fasta scores: E(): 3e-62, 71.01% id in 207 aa.
  
  
 0.969
pgpA
Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
  
 
 0.961
nadR
Similar to Salmonella typhimurium transcriptional regulator NadR SWALL:NADR_SALTY (SWALL:P24518) (410 aa) fasta scores: E(): 1.1e-140, 85.5% id in 407 aa, and to Escherichia coli transcriptional regulator NadR or NadI or b4390 SWALL:NADR_ECOLI (SWALL:P27278) (410 aa) fasta scores: E(): 2.2e-139, 83.9% id in 410 aa.
 
     0.777
mukB
Cell division protein; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily.
  
     0.747
lpxT
Putative membrane-bound phosphatase; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family.
  
  
 0.715
alaE
Putative membrane protein; Exports L-alanine; Belongs to the AlaE exporter family.
  
   
 0.701
ompX
Outer membrane protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri outer membrane protein X precursor OmpX or b0814 or c0900 or z1036 or ecs0892 or sf0765 SWALL:OMPX_ECOLI (SWALL:P36546) (171 aa) fasta scores: E(): 9.1e-40, 66.47% id in 173 aa.
  
    0.690
mtlR
Mannitol operon repressor; Similar to Escherichia coli, and Escherichia coli O6 mannitol operon repressor MtlR or b3601 or c4418 SWALL:MTLR_ECOLI (SWALL:P36563) (195 aa) fasta scores: E(): 2.6e-47, 74.15% id in 178 aa.
  
     0.687
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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