Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA1950Similar to the N-terminal region of Homo sapiens transketolase Tkt or Tkt1 SWALL:TKT_HUMAN (SWALL:P29401) (623 aa) fasta scores: E(): 1.8e-21, 34.22% id in 263 aa, and to Yersinia pestis putative N-terminal region of transketolase ypo3314 SWALL:Q8ZBT1 (EMBL:AJ414156) (276 aa) fasta scores: E(): 3e-96, 88.4% id in 276 aa. (276 aa)    
Predicted Functional Partners:
ECA1951
Putative transketolase C-terminal section; Similar to Escherichia coli 1-deoxy-D-xylulose 5-phosphate synthase Dxs or b0420 SWALL:DXS_ECOLI (SWALL:P77488) (619 aa) fasta scores: E(): 7.6e-18, 30.24% id in 281 aa, and to Yersinia pestis c-terminal region of transketolase ypo3313 SWALL:Q8ZBT2 (EMBL:AJ414156) (314 aa) fasta scores: E(): 2e-97, 80.19% id in 313 aa.
 0.999
rpe
Ribulose-phosphate 3-epimerase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri ribulose-phosphate 3-epimerase Rpe or Dod or b3386 or c4156 or z4739 or ecs4228 or sf3404 SWALL:RPE_ECOLI (SWALL:P32661) (225 aa) fasta scores: E(): 5.1e-71, 83.92% id in 224 aa.
  
 0.996
rpiB
Ribose 5-phosphate isomerase; Involved in catabolism of D-apiose. Catalyzes the isomerization of D-erythrulose 4-phosphate to D-erythrose 4-phosphate.
 
  
 0.978
talA
Transaldolase A; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
    
 0.973
talB
Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
    
 0.973
gapA
Glyceraldehyde 3-phosphate dehydrogenase a; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri glyceraldehyde 3-phosphate dehydrogenase A GapA or b1779 or c2184 or z2818 or ecs2488 or sf1444 SWALL:G3P1_ECOLI (SWALL:P06977) (330 aa) fasta scores: E(): 3.2e-112, 90.6% id in 330 aa; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
    
  0.971
rpiA
Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
    
  0.971
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
  
  
  0.950
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
    
  0.948
tpiA-2
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
    
 0.948
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.