Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
apsIPutative xylose isomerase; Involved in catabolism of D-apiose. Catalyzes isomerization of D-apiose to apulose. (332 aa)    
Predicted Functional Partners:
fruA
Similar to Escherichia coli pts system, fructose-specific IIbc component FruA or PtsF or b2167 SWALL:PTFB_ECOLI (SWALL:P20966) (563 aa) fasta scores: E(): 1.4e-146, 75.13% id in 567 aa.
     
  0.945
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
   
  0.789
aplK
Glycerol kinase; Involved in catabolism of D-apiose. Catalyzes phosphorylation of apulose to form apulose 4-phosphate.
     
 0.777
xylB
Xylulose kinase; Similar to Escherichia coli xylulose kinase XylB SWALL:XYLB_ECOLI (SWALL:P09099) (484 aa) fasta scores: E(): 7.7e-141, 73.81% id in 485 aa.
 
  
 0.732
oiaC
Conserved hypothetical protein; Involved in catabolism of D-apiose. Catalyzes decarboxylation of 3-oxo-isoapionate to L-erythrulose.
  
  
 0.657
ECA1947
Putative sugar-binding periplasmic protein (pseudogene); 1 probable transmembrane helix predicted for ECA1945 by TMHMM2.0 at aa 34-56.
 
     0.651
xylA
Putative D-xylose isomerase; Similar to Escherichia coli xylose isomerase XylA SWALL:XYLA_ECOLI (SWALL:P00944) (440 aa) fasta scores: E(): 1.5e-155, 82.42% id in 438 aa.
  
  
 0.640
ECA1951
Putative transketolase C-terminal section; Similar to Escherichia coli 1-deoxy-D-xylulose 5-phosphate synthase Dxs or b0420 SWALL:DXS_ECOLI (SWALL:P77488) (619 aa) fasta scores: E(): 7.6e-18, 30.24% id in 281 aa, and to Yersinia pestis c-terminal region of transketolase ypo3313 SWALL:Q8ZBT2 (EMBL:AJ414156) (314 aa) fasta scores: E(): 2e-97, 80.19% id in 313 aa.
 
     0.629
lerK
Putative dihydroxyacetone kinase; Involved in catabolism of D-apiose. Catalyzes the phosphorylation of L-erythrulose to L-erythrulose 1-phosphate. Can also phosphorylate D-erythrulose and dihydroxyacetone in vitro.
  
   
 0.618
apnO
Conserved hypothetical protein; Involved in catabolism of D-apiose. Catalyzes the conversion of D-apionate to 3-oxo-isoapionate.
  
   
 0.589
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: high (82%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.