Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cstASimilar to Escherichia coli carbon starvation protein A CstA or b0598 SWALL:CSTA_ECOLI (SWALL:P15078) (701 aa) fasta scores: E(): 8.8e-164, 60.67% id in 684 aa. (687 aa)    
Predicted Functional Partners:
ECA1188
Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yjix or b4353 or c5428 or z5952 or ecs5312 or sf4371 SWALL:YJIX_ECOLI (SWALL:P39395) (67 aa) fasta scores: E(): 4.2e-23, 83.58% id in 67 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein yjix or stm4531 or sty4889 SWALL:Q8XF65 (EMBL:AE008913) (67 aa) fasta scores: E(): 1.1e-22, 83.58% id in 67 aa.
 
  
 0.875
uspB
Similar to Yersinia pestis universal stress protein B UspB SWALL:Q8ZA50 (EMBL:AJ414160) (111 aa) fasta scores: E(): 3.4e-43, 84.68% id in 111 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 universal stress protein b UspB SWALL:USPB_ECOLI (SWALL:P37632) (111 aa) fasta scores: E(): 4.2e-40, 81.08% id in 111 aa.
      
 0.540
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
   
  
 0.535
nhaR
Similar to Escherichia coli transcriptional activator protein NhaR or AntO or b0020 SWALL:NHAR_ECOLI (SWALL:P10087) (301 aa) fasta scores: E(): 2.3e-94, 76.87% id in 294 aa; Belongs to the LysR transcriptional regulatory family.
      
 0.523
csrA
Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). Belongs to the CsrA/RsmA family.
      
 0.515
ECA3410
Similar to Yersinia pestis hypothetical protein ypo3611 or y0263 SWALL:Q8ZB18 (EMBL:AJ414158) (63 aa) fasta scores: E(): 2e-05, 54.54% id in 44 aa.
      
 0.498
ibpB
Heat shock protein B; Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
      
 0.497
uspA
Universal stress protein A; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri universal stress protein A UspA or b3495 or c4293 or z4895 or ecs4367 or sf3526 SWALL:USPA_ECOLI (SWALL:P28242) (143 aa) fasta scores: E(): 6.7e-47, 94.36% id in 142 aa.
      
 0.495
mug
G/U mismatch-specific DNA glycosylase; Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells; Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.
      
 0.495
ispB
Octaprenyl-diphosphate synthase; Similar to Escherichia coli, and Shigella flexneri octaprenyl-diphosphate synthase IspB or Cel or b3187 or sf3227 SWALL:ISPB_ECOLI (SWALL:P19641) (323 aa) fasta scores: E(): 7.9e-100, 83.54% id in 322 aa; Belongs to the FPP/GGPP synthase family.
      
 0.495
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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