STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1966Putative transcriptional repressor; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri transcriptional repressor CytR or b3934 or c4887 or z5481 or ecs4861 or sf4012 SWALL:CYTR_ECOLI (SWALL:P06964) (341 aa) fasta scores: E(): 2.1e-16, 25.88% id in 340 aa, and to Yersinia pestis LacI-family regulatory protein ypo0846 or y3231 SWALL:Q8ZHP4 (EMBL:AJ414145) (360 aa) fasta scores: E(): 2.3e-80, 56.66% id in 360 aa. (356 aa)    
Predicted Functional Partners:
ECA2487
LacI-family transcriptional regulator; Similar to Haemophilus influenzae galactose operon repressor GalR or GalS or hi0821 SWALL:GALR_HAEIN (SWALL:P31766) (332 aa) fasta scores: E(): 5.7e-09, 31.02% id in 303 aa, and to Staphylococcus xylosus probable catabolite control protein A CcpA SWALL:CCPA_STAXY (SWALL:Q56194) (329 aa) fasta scores: E(): 2.5e-08, 26.36% id in 311 aa.
  
     0.773
scrR
Sucrose operon repressor; Similar to Erwinia amylovora repressor scrR SWALL:Q9F497 (EMBL:AJ250722) (342 aa) fasta scores: E(): 4.7e-86, 65.46% id in 333 aa, and to Klebsiella pneumoniae sucrose operon repressor scrR SWALL:SCRR_KLEPN (SWALL:P37076) (334 aa) fasta scores: E(): 5.5e-88, 65.07% id in 335 aa.
  
     0.771
ECA4246
Putative sugar binding transcriptional regulator; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri ribose operon repressor RbsR or b3753 or c4681 or z5254 or ecs4695 or sf3836 SWALL:RBSR_ECOLI (SWALL:P25551) (329 aa) fasta scores: E(): 1.9e-18, 30.63% id in 333 aa, and to Rhizobium meliloti putative transcriptional regulator protein rb0352 or smb20366 SWALL:Q92WI7 (EMBL:AL603643) (334 aa) fasta scores: E(): 8.1e-42, 43.84% id in 317 aa.
  
     0.768
gntR-2
Partial CDS. Similar to the C-terminal regions of Escherichia coli, and Escherichia coli O6 gluconate utilization system Gnt-I transcriptional repressor GntR or b3438 or c4227 SWALL:GNTR_ECOLI (SWALL:P46860) (331 aa) fasta scores: E(): 4.1e-47, 78.36% id in 171 aa, and to Yersinia pestis gluconate utilization system Gnt-I transcriptional repressor gntr or ypo3955 or y3873 SWALL:Q8ZA63 (EMBL:AJ414160) (331 aa) fasta scores: E(): 1.8e-47, 78.94% id in 171 aa.
  
     0.753
gntR
Similar to Escherichia coli, and Escherichia coli O6 gluconate utilization system Gnt-I transcriptional repressor GntR or b3438 or c4227 SWALL:GNTR_ECOLI (SWALL:P46860) (331 aa) fasta scores: E(): 7.1e-94, 74.62% id in 331 aa.
  
     0.748
ECA3772
Similar to Yersinia pestis LacI-family transcriptional regulatory protein ypo2568 SWALL:Q8ZDJ4 (EMBL:AJ414152) (344 aa) fasta scores: E(): 4.7e-70, 54.46% id in 336 aa, and to Escherichia coli O6 putative conserved protein c0337 SWALL:AAN78825 (EMBL:AE016756) (343 aa) fasta scores: E(): 1.6e-67, 56.45% id in 310 aa.
  
     0.709
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
    
 
 0.592
ECA3827
Fructose repressor (catabolite repressor/activator); Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri fructose repressor SWALL:FRUR_ECOLI (SWALL:P21168) (334 aa) fasta scores: E(): 3.9e-114, 85.88% id in 333 aa.
  
     0.590
RhiT
Similar to Erwinia chrysanthemi oligogalacturonide transporter TogT SWALL:Q93KC2 (EMBL:AJ305143) (508 aa) fasta scores: E(): 1.2e-83, 42% id in 519 aa. Also similar to ECA0817 (TogT) (40.426% id. in 517 aa overlap).
 
   
 0.493
ECA1967
Putative hexuronate transporter; Similar to Erwinia chrysanthemi ExuT SWALL:P94774 (EMBL:U86689) (345 aa) fasta scores: E(): 2.6e-53, 42.85% id in 329 aa, and to Yersinia pestis putative sugar transporter ypo0847 or ExuT or y3232 SWALL:AAM86782 (EMBL:AJ414145) (435 aa) fasta scores: E(): 1.2e-142, 77.03% id in 431 aa. Also similar to ECA0644 (44.039% id in 411 aa overlap).
 
     0.491
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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