Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tyrRSimilar to Erwinia herbicola transcriptional regulatory protein TyrR SWALL:TYRR_ERWHE (SWALL:Q9ZIB7) (521 aa) fasta scores: E(): 1.8e-138, 71.12% id in 523 aa. (522 aa)    
Predicted Functional Partners:
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.776
dcd
Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.
      
 0.678
ECA1987
Putative membrane protein; Similar to Escherichia coli, and Escherichia coli O6 hypothetical protein ycjf or b1322 or c1794 SWALL:YCJF_ECOLI (SWALL:P45525) (353 aa) fasta scores: E(): 1.2e-102, 75.28% id in 348 aa, and to Shigella flexneri orf, conserved hypothetical protein ycjf or sf1328 SWALL:AAN42934 (EMBL:AE015159) (353 aa) fasta scores: E(): 1.5e-102, 75% id in 348 aa.
   
 0.639
ECA1986
Conserved hypothetical protein; Similar to Yersinia enterocolitica hypothetical 52.6 kDa protein ycjX SWALL:Q9F4H0 (EMBL:AY008264) (465 aa) fasta scores: E(): 4.4e-166, 81.93% id in 465 aa, and to Escherichia coli hypothetical protein ycjx or b1321 SWALL:YCJX_ECOLI (SWALL:P76046) (465 aa) fasta scores: E(): 1.1e-154, 76.34% id in 465 aa.
  
  
 0.582
xni
Exodeoxyribonuclease IX; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
      
 0.545
gcvP
Putative glycine cleavage system P protein (glycine dehydrogenase [decarboxylating]); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.524
trpS
tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.516
tyrA
Similar to Escherichia coli T-protein [includes: chorismate mutase and prephenate dehydrogenase] TyrA or b2600 SWALL:TYRA_ECOLI (SWALL:P07023) (373 aa) fasta scores: E(): 1.6e-123, 87.13% id in 373 aa.
      
 0.502
dnaA
Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
      
 0.488
ECA1988
Putative peptidase; Similar to Deinococcus radiodurans arge/dape/acy1 family protein dr2025 SWALL:Q9RSU7 (EMBL:AE002039) (459 aa) fasta scores: E(): 3.4e-22, 29.93% id in 471 aa, and to Oceanobacillus iheyensis hypothetical conserved protein ob1111 SWALL:BAC13067 (EMBL:AP004596) (453 aa) fasta scores: E(): 8.2e-21, 29.91% id in 478 aa.
       0.486
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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