STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpxThiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (167 aa)    
Predicted Functional Partners:
sodA
Manganese superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.757
ompA
Outer-membrane protein A; Similar to Erwinia carotovora putative outer-membrane protein a precursor OmpA SWALL:Q9RM69 (EMBL:AJ249340) (367 aa) fasta scores: E(): 2.6e-120, 90.32% id in 372 aa, and to Serratia marcescens outer membrane protein a precursor OmpA SWALL:OMPA_SERMA (SWALL:P04845) (359 aa) fasta scores: E(): 4.8e-71, 75.61% id in 369 aa; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
  
 0.610
ECA1991
Similar to Yersinia pestis hypothetical protein ypo2340 or y1992 SWALL:Q8ZE44 (EMBL:AJ414152) (256 aa) fasta scores: E(): 5.7e-69, 73.93% id in 234 aa, and to Shigella dysenteriae YcjI SWALL:Q9LA26 (EMBL:AF153317) (262 aa) fasta scores: E(): 1.4e-67, 70.08% id in 234 aa.
       0.558
ECA2649
Thioredoxin reductase.
  
  
 0.519
ECA1117
Probable peroxidase; Similar to Yersinia pestis putative alkyl hydroperoxide reductase subunit C AhpC or ypo3194 or y0988 SWALL:AAM84569 (EMBL:AJ414155) (200 aa) fasta scores: E(): 2.6e-76, 91.5% id in 200 aa, and to Vibrio vulnificus peroxiredoxin vv10453 SWALL:AAO08975 (EMBL:AE016798) (202 aa) fasta scores: E(): 1.4e-61, 73.5% id in 200 aa.
  
  
 0.484
ahpC
Alkyl hydroperoxide reductase C22 protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
  
 0.484
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
    0.483
norV
Anaerobic nitric oxide reductase flavorubredoxin; Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family.
     
 0.451
clpX
ATP-dependent Clp protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
  
  
 0.442
ECA3349
Similar to Yersinia pestis putative sigma 54 modulation protein ypo3279 SWALL:Q8ZBV5 (EMBL:AJ414156) (120 aa) fasta scores: E(): 3.7e-34, 84.95% id in 113 aa, and to Salmonella typhimurium, and Salmonella typhi ribosome associated factor, stabilizes ribosomes against dissociation yfia or stm2665 or sty2853 SWALL:Q8XEX6 (EMBL:AE008821) (112 aa) fasta scores: E(): 8.3e-31, 79.46% id in 112 aa.
   
    0.436
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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