STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
tpxThiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (167 aa)    
Predicted Functional Partners:
sodA
Manganese superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.705
ompA
Outer-membrane protein A; Similar to Erwinia carotovora putative outer-membrane protein a precursor OmpA SWALL:Q9RM69 (EMBL:AJ249340) (367 aa) fasta scores: E(): 2.6e-120, 90.32% id in 372 aa, and to Serratia marcescens outer membrane protein a precursor OmpA SWALL:OMPA_SERMA (SWALL:P04845) (359 aa) fasta scores: E(): 4.8e-71, 75.61% id in 369 aa; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
  
 0.630
fur
Ferric uptake regulation protein; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 ferric uptake regulation protein Fur or b0683 or c0770 or z0831 or ecs0714 SWALL:FUR_ECOLI (SWALL:P06975) (148 aa) fasta scores: E(): 9.2e-52, 91.09% id in 146 aa; Belongs to the Fur family.
   
  
 0.589
ECA1991
Similar to Yersinia pestis hypothetical protein ypo2340 or y1992 SWALL:Q8ZE44 (EMBL:AJ414152) (256 aa) fasta scores: E(): 5.7e-69, 73.93% id in 234 aa, and to Shigella dysenteriae YcjI SWALL:Q9LA26 (EMBL:AF153317) (262 aa) fasta scores: E(): 1.4e-67, 70.08% id in 234 aa.
       0.559
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
    0.552
ECA3349
Similar to Yersinia pestis putative sigma 54 modulation protein ypo3279 SWALL:Q8ZBV5 (EMBL:AJ414156) (120 aa) fasta scores: E(): 3.7e-34, 84.95% id in 113 aa, and to Salmonella typhimurium, and Salmonella typhi ribosome associated factor, stabilizes ribosomes against dissociation yfia or stm2665 or sty2853 SWALL:Q8XEX6 (EMBL:AE008821) (112 aa) fasta scores: E(): 8.3e-31, 79.46% id in 112 aa.
   
    0.545
hmpX
Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.
      
 0.542
ECA2252
Similar to Escherichia coli probable oxidoreductase ydfg or b1539 SWALL:YDFG_ECOLI (SWALL:P39831) (248 aa) fasta scores: E(): 2.3e-73, 78.62% id in 248 aa, and to Salmonella typhimurium, and Salmonella typhi hypothetical oxidoreductase ydfg or stm1511 or sty1550 SWALL:YDFG_SALTY (SWALL:P40864) (248 aa) fasta scores: E(): 2.6e-73, 77.73% id in 247 aa; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
    0.533
ECA4481
Similar to Agrobacterium tumefaciens short-chain dehydrogenase atu4280 or agr_l_1165 SWALL:Q8U819 (EMBL:AE009356) (259 aa) fasta scores: E(): 9.9e-61, 66.12% id in 245 aa, and to Ralstonia solanacearum probable oxidoreductase protein rsp0935 or rs05398 SWALL:Q8XRC3 (EMBL:AL646081) (250 aa) fasta scores: E(): 4.9e-67, 70.56% id in 248 aa; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
    0.533
lepB
Similar to Escherichia coli signal peptidase I LepB or b2568 SWALL:LEP_ECOLI (SWALL:P00803) (324 aa) fasta scores: E(): 4.7e-93, 69.75% id in 324 aa; Belongs to the peptidase S26 family.
   
    0.532
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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